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Top 12 Nootropics

Updated on May 26, 2017

More and more nootropics are coming out as people come to realize their benefits in terms of improving memory and other cognitive functions. But for all the products and supplements that emerged in 2015, only a few can be considered as the best. If you want to know what the top nootropics for 2015 are, take a look at our list below.

An Introduction to Nootropics

1. Peptides

Many top rated nootropics have come and gone, but peptides are still around and with good reasons. Simply put, peptides are very effective in terms of improving memory, learning and focus. Various types of peptides have emerged, but one of the most powerful is N-phenylacetyl-L-prolylglycine ethyl ester (Noopept), which was formulated in Russia and partly drawn from racetams.

There are a lot of potent nootropics available, but peptides have earned a reputation for being a thousand times more powerful than racetams. Highly bioavailable, these are among the best nootropics when it comes to going through the blood and brains.

2. Ampakines

Next in our list of the best nootropics 2015 is ampakines, which stimulates acetylcholine receptors and improves memory, motivation and other vital cognitive functions. Ampakines are still somewhat new, but there’s already extensive research done which shows that it has a significant effect on cognitive function and when combined with other nootropics, cognitive improvements are accelerated.

3. Choline & Acetylcholine Intermediates

No list of the top nootropics for ADHD will be complete without mentioning choline as they figure prominently in stimulating brain receptors. There are many types of choline nootropics, but the most powerful are Centrophenoxine, Alpha GPC and Citicoline, all of which improve cognitive functions without side effects.

While there are different types of choline, you will only receive maximum benefits if the most variants are consumed. The more powerful ones however, may produce temporary side effects like insomnia for the first few days, but this will dissipate and you’ll then feel the full effect.

4. Vitamin B Nootropics

Check the ingredients of the best nootropics smart pills today and you will see vitamin B derived nootropics like pyritinol and sulbutiamine mentioned, and that’s not surprising as these compounds increase energy, memory and improves your mood. These supplements should not be confused with regular B vitamins however, as they are different.

Vitamin B derivatives are potent as standalone nootropics, but they’re also worth combining with others to amplify the power and effect. The primary benefit of these vitamin B derivatives is improved memory retention as mentioned above, but because of its B properties, also enhances your immune system.

5. Caffeine + L-Theanine

Number 5 on the list of our best natural nootropics is caffeine and L-theanine. On their own these are among the most powerful cognitive nootropics available, but when taken together become even more potent. L-Theanine in particular does a good job in mitigating the negative effects of excess caffeine.

By mixing this nootropic with a cognitive enhancer (caffeine), you’ll have greater focus, motivation, improved mood, and better alpha wave levels, which in turn will put you in a relaxed state of mind.

6. Creatine

If you read any best nootropics review you’re likely going to find creatine there because it does as much for your cognitive function as for your muscles. As a nootropic, creatine improves recall and concentration, at the same time improving ATP synthase in the brain, which leads to short and long term memory improvement.

ATP Synthase: The Power Plant of the Cell

7. Bacopa Monnieri

Bacopa Monnieri also provides short and long term memory retention benefits, and there is also evidence that it reduces anxiety when consumed on a consistent basis. Tests also reveal bacopa monnieri increases alertness like caffeine but without the side effects and more significantly, several clinical trials have demonstrated that people who take bacopa regularly have better reasoning skills than those who don’t.

8. Choline

No surprises here because for the longest time choline has been used as a primary nootropic. Although choline has been around for a while, it still earns a place in the top 12 because of its role in augmenting memory formation. While choline is available in foods, most people don’t get enough of it, making supplementation necessary.

Whether taken alone or in combination with other nootropics, the net effect of choline is improved memory for young people and the elderly, and if you’re in it for the long term, it also helps fight brain related health conditions and neuro-degenerative diseases.

9. Rhodiola Rosea

One of the keys to keeping your memory sharp is being fit and energetic, and that’s what this natural nootropic does. Its primary benefit is providing energy, and there’s a good amount of anecdotal and scientific evidence which indicates that chronic usage leads to greater reasoning skills and faster reaction time.

10. Asian Ginseng

There are many types of ginseng, but insofar as improving memory and focus are concerned this is the best available. The number of benefits it provides are very extensive but the most important when it comes to cognitive functions are better memory recall, increased physical and mental endurance, less anxiety and improved mood.

11. CILTeP

Making it to number 11 on our list is CILTeP. This is a fairly new nootropic, and CILTeP, (chemically induced long-term potentiation) combines forskolin and artichoke extract to produce a special substance that inhibits PDE-4 and improves cAMP. When taken on a regular basis, this nootropic will enhance your memory, concentration and heighten alertness.

12. Piracetam

Last but not the least is piracetam. If you’ve been taking nootropics for a while then you’ve no doubt have of this one, as this is the very first labeled nootropic back in 1972. While piracetam has been around for a while now, it still deserves a place in our top 12 because it continues to deliver in terms of improving memory, motivation and getting an energy boost.


So which of these nootropics is the best and should be taken on a regular basis? The ideal scenario is to take each one, but the good news is that many nootropic brands have these very ingredients so you with just one tablet or capsule you’ll have all the essential nootropics you need.

What do you think is the best nootropic we didn't mention here? Do you have some experiences with these nootropics above? Please share in the comment section below. Thanks!

© 2015 Dave Brik


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