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What Is The Difference Between L-Theanine And L-Glutamine?

Updated on March 24, 2010

What Is The Difference Between L-Theanine And L-Glutamine?

Theanine is a modification of the amino acid namely glutamine with an ethyl group added. The glutamate is a starting material in the reaction that looks similar to this:

L-glutamate + ATP + ethylamine results in phosphate + ADP + L-theanine

This reaction occurs in the tea roots, thus theanine is transported to leaves of the tea plant. A similar reaction, using an enzymatic catalyst, is used to synthesize L-theanine on a commercial basis.

What is L-Theanine?

L-theanine is an amino acid found in the tea plant and it is also a dietary supplement that is claimed to have beneficial impact on the treatment of high blood pressure, stress, anxiety, and Alzheimer's disease. L-theanine powder may increase the levels of serotonin and GABA in the blood, reduce norepinephrine levels, and protect brain nerves from damage often occuring in Alzheimer's disease. You should be aware, that though L-theanine has proved to have positive effects on animals, little studies has been done in humans and there is not enough evidence to confirm the supplement’s effectiveness.

What is L-Glutamine?

L-glutamine is a non-essential amino acid naturally produced by the human body. This compound can be found in numerous protein-rich foods and is available in the form of dietary supplements that are claimed to help in several health conditions, including anxiety, insomnia, and depression. L-glutamine plays an important role in proteins and other amino acids build-up. In addition to its ability to build proteins, the supplement has several other functions in the body serving as a fuel for various cell types in the body, including immune cells.

Further Readings:

What is l-theanine used for?
Can l-theanine cause anxiety?
Can l-theanine cause kidney problems?

Can you buy l-theanine in bulk?
Does l theanine affect the liver?
How long has l theanine been studied?
How much theanine in drinks?

Is theanine harmful for heart patients?


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