Dunno. Seems to me, the only thing should be depressed after you pee, is the Flush button.
Or, maybe you're just taking the piss outta the whole subject?
Oh, if you're not English, Australian, some others, you won't know what 'taking the piss' means.
It means making a joke out of it.
Maybe that's the way I've (wrongly) interpreted your (serious) question.
If so, I'm sorry. I certainly know how serious depression can be.
But I still don't know the answer.