Restless leg syndrome, or RLS, is a neurological disorder that can affect not only the legs, but also the arms, and/or torso. Amputees have been known to suffer this disorder as well. It is most commonly associated with iron deficiency, pregnancy, diabetes, autoimmune diseases, fibromyalgia and peripheral neuropathy.
Several treatments have been found to alleviate the symptoms. Gapabentin (neurontin), dopamine agonists such as Requip, and opiate pain killers are the main prescription treatments.
I personally suffer from RLS, and it started when I was pregnant and reoccurs occasionally, usually around a migraine. What really helps me is potassium, black cohosh and a pain med I take called ultram. Low levels of serotonin is what triggers my RLS, so anything that raises my serotonin alleviates the symptoms. Black cohosh and ultram both increase serotonin levels. I'm not sure why the potassium works, unless it has something to do with blood pressure.
Hope that helps.