I was on Nexium twice a day for gastritis and acid reflux. We are talking pain so bad it would wake me in the middle of the night. Like I ate hot sand. Because of insurance, I had to swtich to Prevacid (it works almost as well). The Nexium really worked for me. I still had some reflux (more a mechanical issue than acid). After a year on Nexium my gastritis and Barrett's Esophagus were even healed. If you are not sure what Barrett's is, look it up. It's not good. And being in my 30's I am way to young to be getting that!