I can take imitrex now and get rid of my migraine as long as I also get quiet, lay down in a dark room and put the a/c down to 65 degrees. I had them every day for three months straight about 20 years ago. It was horrible. I couldn't eat and I thought I was going to waste away and die. I finally got put on cafergot that got me out of that pain cycle. Back then they use to put phenobarbitral in the cafegot and it worked great and fast, but now they don't put phenobarbitral in cafergot. But I did switch to the other cafergot and it did help. I was on that therapy for years and years. Then finally I started on Imitrex and now I only get a migraine at the most once a month. I think though the reduction in my migraine is due to menopause. Migraines are not the same in every body and what works for some does not work for others. I come from a family that suffers from them, so mine have a genetic componet. I feel the pain for anyone who suffers from migraines.