I do not know. I really never had a master plan for my life. I wanted to finish college, get marry, children and a good job. I did not try to fill in any of the details around those major events, which have often been surprising, happy and disappointing over the years.
Therefore, I cannot give a yes or no answer. Life was never meant to be that predictable--it would actually be pretty boring. Certainly, we have all faced situations we wished we could have avoided--death of parents, spouse, friend, loss of job, financial troubles, natural disasters...but we do go on.