Milk Thistle has been shown to rejuvenate the liver, and kidneys. avoid alcohol, and high fat foods. The b complex vitamins help to utilize, instead of store fat. It is a co factor in how the body uses good fats, such as krill, fish, and flax. If you have a kidney, or liver problem it is best to consult a physican before starting any new vitamin regimen. The liver filters all of the substances that we put into our body, the way to bypass it is sublingual. Therefore a liquid milkthistle, a couple of drops, under the tongue might be advisable if there is a problem already.