That varies from person to person. Some people have physical problems they weren't aware of. Then, when they exercise, the physical issues appear to cause serious injuries. These hidden problems might be asthma, weak heart, clogged arteries, etc.
The best thing is to have a thorough medical checkup. Then start with an exercise program that is slow and within your physical limitations. Drink plenty of fluids -- water is the best -- and rest every other day.
Also, be aware of what your body is telling you. If you feel pain in your knees or ankles, or you are breathing too heavily, then something isn't right. One mistake people make is jogging right away. Start out by walking. Slowly increase the distance and tempo until you reach a slow jog. And try to jog on dirt or grass. Jogging on cement, even with cushioned shoes, can damage your ligaments and muscles.
No exercise program fits everybody. So do what's best for you.