The fear if you make a change everything can go wrong, it can alter everything in your life by one wrong change. I think humans (in my opinion) are so hesitant is because we don't know anyone else better than we know ourselves, in reality we can never know anyone as well as we know ourselves... what I'm trying to say out of this is I think people are afraid of the decision that lies ahead of what we are "hesitating" on... for instance our gut says we should go home instead of partying, we decide not to and something tragic happens... a wreck, someone brings a gun, lots of drugs and the cops show up. One change can change your life forever... and that's why us humans are SO hesitant on everything we do.
Our hesitance is what makes us who we are, it's something no other mammal has and ever will, it keeps us safe (sometimes) and puts us in danger at other times... it's what makes it absolute and also... in the strangest of ways, makes us a better person or in the worst case... can ruin your life... so I think we should keep hesitating or next time were asked "Go jump off a bridge"... we do just that.
I hope this helps, this was "MY" opinion, everyone has there own, and none are wrong. Thanks for sharing PM and GREAT question!