yes, there are several things you can do, i even wrote a hub about it.
Thing you need to consider tough, is when you have a tootache, you still need to see a dentist.
But, if a pain killer doesn't work, or not fast enough, i used to take a mouthfull of brandy, bourbon, or anything strong alcoholic. Hold the drink onto your sore tooth, and it will sedate the tooth, for a while, if you take a painkiller short before, or after, you will get a nice relief.
You can also visit my hub for more tips, in case this one doesn't help.
Hope this can help you out.