Stem Cell Releasing Products Could Be Dangerous.
HERE'S WHAT I THINK
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Stem Cell Releasing Products Could Be Dangerous.
The body is an amazing balance of cycles and systems. When out of balance, the results are not usually good. When I first found a lens here promoting a stem cell releasing product, my first thought was "stem cells don't belong in the peripheral blood system in large quantities".
In 1994 I was a aware that Super Blue Green Algae is Aphanizomenon flos-aquae, and that in many oceans, that's red tide. Yup, toxic.
Now, the Klamath products are safety tested, and indeed, pass tests. However, you can only test for what you know to test for.
I'm not saying that StemEnhance is carcinogenic, but I do think that there are potential dangers in increasing your bone marrow stem cell release.
Below I will present the health benefits and safety of Spirulina, another cyanobacteria (blue-green algae). If you're looking for natural health supplements, Spirulina could be exactly what you're looking for without the risks.
I also just searched ClinicalTrials.gov, and found that the only algae product listed in the clinical trials Phase III ("Comparative studies to verify the effectiveness of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques determined in phase II studies") is Dunaliella algae, and another algae product in official clinical trial (phase not listed) is ProAlgaZyme. I'll be exploring these more also, as it's always good to have a truly safe alternative treatment.
Bone Marrow Stem Cells Are Part of a Delicate Balance, Not a Magic Bullet! - If you have enough CD34+ cells in your peripheral blood, your hematologist may thin
Check out StemEnhance: The Rest of the Story for a very well written indication of the problems.
Here's the intro paragraph:
The following story first appeared as a Wellness Update on February 14, 2007. On February 24, 2007 I received a lengthy response from Christian Drapeau, the creator of StemEnhance. He assured me that he has research ready for publication that will demonstrate that StemEnhance continues to regularly stimulate bone marrow stem cell release when taken over a two year period. Unfortunately he expressed a total disregard for the potential toxicity of the product and a complete lack of appreciation of the manner in which bone marrow stem cells promote cancer growth and metastases. Mr. Drapeau's remarks are posted in their entirety following the original article, with my comments in blue.
Why would you want so many stem cells being released on a regular basis? Check out StemEnhance: The Rest of the Story
Stem Cell Releasing Products Could Be Dangerous.
Yes, you're right!
Closed Guestbooks on many stem cell related lenses on Squidoo
Or why the marketers don't want you to know the truth.
I got started on this lens because of another lens I read. I added a comment, but the comment was never approved. The lensmaster decided to email me a response. I'm posting it here, because another stem cell lens I went to also only posts approved comments.
Hey, you're famous!
Someone was just checking out your Squidoo lens "Flow Cytometry Courses" and wrote you the following note...
">>The point of stem cells is that when they divide, one stays a stem cell, and the other goes on to become what the body needs. Pluripotent stem cells are CD34+ , but this cell membrane marker is also how we distinguish "blasts" in acute leukemia!
Please list the references from your upper text box. Stem cell research is fascinating and important.<<
Thank you for your inquiry! We do have references to our articles, below each article. The scientist who have discovered this also have articles published in medical journals. There is more information about the stem enhancing product through the manufacturer.
New England Journal of Medicine September 8, 2005. Volume 353:999-1007. Number 10
Circulating Endothelial Progenitor Cells and Cardiovascular Outcomes By
Nikos Werner, M.D., Sonja Kosiol, M.D., Tobias Schiegl, M.D., Patrick Ahlers, M.D., Katrin Walenta, M.D., Andreas Link, M.D., Michael BÃ¶hm, M.D., and Georg Nickenig, M.D.
Cardiovascular Revascularization Medicine paper published. Mobilization of human CD34+CD133+ and CD34+CD133- stem cells in vivo by consumption of an extract from Aphanizomenon flos-aquae - related to modulation of CXCR4 expression by an L-selectin lignand? By Gitte S. Jensen, Aaron N. Heart, Lue A.M. Zaske, Christian Drapeau, Niraj Gupta, David J. Schaeffer, J. Alex Cruickshank. Cardiovascular Revascularization Medicine Volume 8, Issue 3, July-September 2007, Pages 189-202.
Triple-Blind Randomized Placebo-Controlled Study of the Effect of StemEnhance on Bone Marrow Stem Cell Mobilization by Christian Drapeau, MSc. www.healthylivingstuff4u.com/tripleblindstudy.pdf
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StemEnhance Risks - Your body's balance tells your bone marrow when to release stem cells just fin.
- StemEnhance: The Rest of the Story
A very well written piece of correspondence that brings up some of the issues you need to think about if you're considering taking a stem cell releasing product.
- PubMed Abstract of 'Bone marrow-derived cells: roles in solid tumor. Minireview.'
Xiong-Zhi W, Dan C, Guang-Ru X. Bone marrow-derived cells: roles in solid tumor. Neoplasma. 2007;54(1):1-6. "The role of cancer stem cells has been demonstrated for some cancers. Recently, research indicated that solid tumors may originate from bone
- Role of hematopoietic lineage cells as accessory components in blood vessel formation
Takakura, N. Role of hematopoietic lineage cells as accessory components in blood vessel formation. Cancer Sci. 2006 Jul;97(7):568-74. "It is widely believed that after birth, endothelial cells (EC) in new blood vessels are derived from resident EC o
- Stem Cells and Neurogenesis in Tumors
Bone-marrow-derived and tissue-resident stem cells promote repair of injured tissues by contributing to new blood vessel, muscle and nerve formation. These same stem cells may contribute to tumor growth and spread. Tumors express numerous growth fact
- NIH Stem Cell Information Home Page
A thorough resource on stem cells from the National Institutes of Health. The basic facts of stems cells is well worth reading. Adult stem cells are an exciting medical possibility, but not yet well understood enough to know whether having a 30% incr
Beware the Leap Between Animal Models and Your Body's Balance
Stemulite, another stem cell enhancing product NOT based on AFA also claims that its ingredients "can be used as a potent recruiter and mobilizer of stem cells from the bone marrow."
Here's a paragraph explaining one of their formula's ingredients: "Once stem cells become resident of a tissue system (such as a muscle group) or organ they quickly multiply and replace old tissue with new juvenile cells which are able to mature in a matter of hours or days into the same tissue type that was earlier dysfunctional. If the genetic component of the tissue is normal, the new cells continue replicating indefinitely, completely and perminately (SIC) eradicating the problem. In the case of fitness training, the stem cells are recruited in great numbers to mobilize in muscle systems replacing fat and adding brand new muscle."
Okay, let's look at this more carefully.
"Once stem cells become resident of a tissue system (such as a muscle group) or organ they quickly multiply and replace old tissue with new juvenile cells which are able to mature in a matter of hours or days into the same tissue type that was earlier dysfunctional." This has not been shown conclusively in humans, and even the rat data is contradictory.
"If the genetic component of the tissue is normal, the new cells continue replicating indefinitely, completely and perminately eradicating the problem."
If. That's a big if today. Secondly, if new cells continue replicating indefinetly, they are called immortal, and a clone. In cancer, cells are immortal clones. In our tissues, there is a natural aging process of cells that takes place.
There is no proof that an increased stem cell release to your peripheral blood system is a good thing. Please be careful.
Aphanizomenon flos-aquae aka Super Blue Green Algae - My axe has been grinding since 1994
Just because it's "natural" doesn't mean it's healthy for you.
- Concentrations of particulate and dissolved cylindrospermopsin in 21 Aphanizomenon-dominated tempera
Abstract about examining AFA in German lakes.
- llergenic (sensitization, skin and eye irritation) effects of freshwater cyanobacteria - experimenta
Microcystis, Anabaena, Cylindrospermopsis, and Aphanizomenon bloom and strain samples were examined in sensitization and irritation tests and no correlation was found between the toxin content and the allergenic character. The most toxic one (Microcy
- Assessing potential health risks from microcystin toxins in blue-green algae dietary supplements.
Many of these products contain Aphanizomenon flos-aquae, a BGA that is harvested from Upper Klamath Lake (UKL) in southern Oregon, where the growth of a toxic BGA, Microcystis aeruginosa, is a regular occurrence. M. aeruginosa produces compounds call
- Multiplex PCR for the detection of toxigenic cyanobacteria in dietary supplements produced for human
The production of food supplements containing cyanobacteria is a growing worldwide industry. While there have been several reports of health benefits that can be gained from the consumption of these supplements, there have also been a growing number
Spirulina is safe, nutritional, and scientifically interesting.
It just floats on your drinks and doesn't dissolve, but it's good for you.
Spirulina is another cyanobacteria, or blue-green algae that has been grown as a food and nutritional supplement for years.
Unlike the safety aspects of Aphanizomenon flos-aquae, spirulina species have repeatedly been shown to besafe,the vitamins, minerals, and proteins to be bioavailable,and even to be interesting genetically!
Below I present links to scientific abstracts and online information to show you that whatever you're looking for that's safe in Aphanizomenon flos-aquae, you'll find in spirulina.
Read Up On Spirulina - To Your Health! - The only controversy is whether the claims are too grandiose.
You can't overdose on it.
It's not contaminated with possible neurotoxins or possible hepatotoxins.
It's good for what ails you. And believe me, if you like any of the sea vegetables, you can enjoy the taste of spirulina, also.
- Latest Scientific Research on Spirulina:
This Spirulina Health Library contains over 100 published scientific references covering 30 years of international research. It is solely for education. It is not intended as medical advice or as a guide for self-treatment. Consult a qualified health
- Bioremediation potential of spirulina: toxicity and biosorption studies of lead
CONCLUSION This study led to the conclusion that spirulina's rapid lead adsorption rate and high lead adsorption capacity made them well suited for the removal of lead in wastewater. In addition, living cells of spirulina were found to have high tol
- [Pharmacology and toxicology of Spirulina alga]
Spirulina, a unicellular filamentous blue-green alga has been consumed by man since ancient times in Mexico and central Africa. It is currently grown in many countries by synthetic methods. Initially the interest in Spirulina was on its nutritive val
- C-phycocyanin ameliorates doxorubicin-induced oxidative stress and apoptosis in adult rat cardiomyoc
Doxorubicin (DOX), a potent antineoplastic agent, poses limitations for its therapeutic use due to the associated risk of developing cardiomyopathy and congestive heart failure. The cardiotoxicity of doxorubicin is associated with oxidative stress an
- Inhibitory effects of Spirulina in zymosan-induced arthritis in mice.
The anti-inflammatory effect of microalgae Spirulina was studied in zymosan-induced arthritis in mice. Four days after the intra-articular injection of zymosan (15 mg/ml), Spirulina (100 and 400 mg/kg perorally) was administered to animals for 8 days
- Nutritional and therapeutic potential of Spirulina.
Spirulina, a filamentous cyanobacterium, possesses diverse biological activities and nutritional significance due to high concentration of natural nutrients, having bio-modulatory and immuno-modulatory functions. Different Spirulina preparations infl
- Spirulina fusiformis provides protection against mercuric chloride induced oxidative stress in Swiss
Oxidative stress induced by mercuric chloride (5 mg/kg body weight i.p.) in mice substantially increases the lipid peroxidation level along with corresponding decrease in the reduced glutathione and various antioxidant enzymes in liver and increase i
- Spirulina on MedlinePlus
Spirulina is a rich source of nutrients, containing up to 70% protein, B-complex vitamins, phycocyanin, chlorophyll, beta-carotene, vitamin E, and numerous minerals. In fact, spirulina contains more beta-carotene than carrots. Spirulina has been used
What's the name of your blud-green algae?
To sum, if you are looking for anti-cancer, anti-viral, immune system strengthening, anti-oxidant, anti-inflammatory, and even heavy metal scavenging activity in a natural supplement, try Spirulina. Stay away from AFA, Super Blue Green Algae from Klamath Lake,Aphanizomenon flos-aquae for safety concerns.
If you think that increasing your bone marrow stem cell circulation by 30% sounds like a keen idea, please speak with your local hematologist or fully trained naturopathic ND. You don't have to take my word for it. Your body knows best which cells need to be made at any given time.