ArtsAutosBooksBusinessEducationEntertainmentFamilyFashionFoodGamesGenderHealthHolidaysHomeHubPagesPersonal FinancePetsPoliticsReligionSportsTechnologyTravel

THANKSGIVING PHARMACOLOGY - The SCIENCE inside our Thanksgiving Meal

Updated on November 29, 2011

Thanksgiving Pharmacology

Ah...Thanksgiving Day. Of all our annual festivals, surely none stimulates the pens of ready writers like this most happy Holiday.

  • Culinary Experts write about their latest Thanksgiving recipes
  • Decorating Experts write about their creative Thanksgiving styles
  • History Experts tell us all about the Pilgrims and the origins of this delicious day

But pharmacists? Surely this is one celebration for which our humble profession must simply stand back, content to be observers to the plethora of pages being written by others.

Not so fast! Actually, believe it or not, there is A LOT going on pharmaceutically while we sit around our dinner tables and enjoy the traditional Thanksgiving fare. And so I dedicate this article to Thanksgiving Pharmacology - the science inside our Thanksgiving meal.

Allow me to briefly take you on a guided tour around your table and explore a virtual panoply of pharmaceutical facts.

TURKEY & L-Tryptophan

YAWN...we all know it's coming. Shortly after consuming that 3'rd BIG helping of this beautiful bird we are all ready for a Thanksgiving day afternoon nap. But why?

The answer we have all been somewhat conditioned to give is "L-tryptophan!" Yes, we have all been taught to blame our tiredness on the Turkey...and the fact that turkey meat has L-tryptophan (an amino acid known to cause drowsiness) makes it a closed case.

But is that fair? Is the bird really to blame for your late day lethargy?

Some Facts: L-Tryptophan is converted to substances (melatonin especially) in the brain which can cause drowsiness. This is true. But in order for Tryptophan to reach the brain it needs to be consumed with a relatively low amount of protein. The reason is that proteins are made of many amino acids, all of which are competing for entrance to our brains. The more total protein (i.e. turkey and other meats)...the less tryptophan gets in. all likelihood...all that protein you just ate actually PREVENTED tryptophan from causing you drowsiness!

So why then this drowsiness after our Thanksgiving Feast? Well, probably for the same reasons we would be drowsy any time we consume an enormous number of calories in a short amount of time. Digestion diverts blood toward our stomachs, causing a drowsy/dizzy feeling. Carbohydrates (like those mashed potatoes and sweet potatoes and rolls!) make use sleepy. And fats (yep...I'm sure we ate some fat) are harder to digest and thus consume more energy, making us sleepy.

So in all fairness to our (formerly) feathered friend...lets not blame him for our slumber this year.

CRANBERRY SAUCE & Polyphenols!

Turkey isn't the only pharmaceutically interesting dish being served on Thanksgiving. That cranberry sauce that Aunt Mary just passed you for the 4th time is loaded with POLYPHENOLS!

What are Polyphenols you say? I thought you would never ask! Polyphenols are terrific antioxidants, and antioxidants have been studied for a variety of benefits including:

  • Weight loss
  • Reducing Blood Pressure
  • Arthritis
  • Memory and Concentration

The polyphenols in cranberries have twice the antioxidant power of Vitamin C and nearly 5 times the antioxidant power of Vitamin E. So...if you're not too tired yet...would you mind passing me the cranberries?

SWEET POTATOES & Beta carotene

Although white potatoes are consumed in much greater quantities, the sweet potatoe was actually introduced to America 100 years earlier, possibly by Christopher Columbus himself. This vegetable is far more than a simple Thanksgiving tradition. Sweet potatoes are an excellent source of an essential vitamin - vitamin A.

There is some cool pharmacology here. Those sweet potatoes which Grandma always brings, covered in marshmallows - almost like eating desert with dinner- are loaded with a substance called "beta carotene." Ever wonder why sweet potatoes are bright orange? Sure you have! And the answer is, you guessed it, beta carotene. By the way, in case you were wondering, the name "carotene" came about when a scientist isolated this substance from carrots (carrot roots to be more precise)!

Beta carotene is converted in our bodies to Vitamin A. It is a neat process which requires oxygen and a specific enzyme (a monooxygenase) and transforms beta carotene into 2 nice Vitamin A (retinal) molecules. Vitamin A is absolutely essential for proper vision and other important bodily functions.

By the way, beta carotene is much better absorbed when combined with some fat. So drizzling some butter over those sweet potatoes is not merely a "taste" enhancer, but an important Vitamin A enhancer as well! So go ahead, ask someone to pass you another serving of Grandma's sweet potatoes! Do it for your health!

True cinnamon pictured on the left side
True cinnamon pictured on the left side

PUMPKIN PIE & cinnamon

Well...nothing rounds off our Thanksgiving meal like a slice of pumpkin pie. Soft and spicy, this holiday treat is a sweet tradition on our holiday table. But what is going on underneath and inside this delicious dessert? One pharmaceutically interesting ingredient found in nearly every pumpkin pie recipe is CINNAMON!

Cinnamon is a spice that comes from the inner bark of the cinnamon tree. Yep...cinnamon is basically tree bark! Most of the world's cinnamon comes from Sri Lanka. True cinnamon, also known as Ceylon cinnamon, tends to be more expensive than its less expensive cousin, cassia cinnamon.

Pharmaceutically, true cinnamon (ceylon) is a better choice. Studies have been done to indicate it is useful in lowering blood sugar for type 2 diabetes, as well as potential benefits on blood cholesterol. The less expensive, cassia, cinnamon is known to have higher amounts of "coumarins" which have anticoagulant properties and could be dangerous in high dosages.

How can you know which cinnamon was used in your pumpkin pie? True cinnamon (the better stuff) when obtained as cinnamon sticks, will have multiple thin layers off the bark if you look at it on the end. Cassia cinnamon will look more like 1 thick circle. Another possible test for true cinnamon is to administer a drop of iodine tincture to the powdered cinnamon. True cinnamon, which contains very little starch, will not change in appearance. Cassia, which has a higher starch content, will change in color to a deeper blue tint (this is due to the amylose molecules in starch reacting with the iodine). Cool science...right inside your pumpkin pie!!

Thanksgiving and Science

Well, I hope this brief tour of the pharmaceutical qualities and science inside your Thanksgiving meal have not detracted from the enjoyment of this holiday.

We all have much to be thankful for. As my pastor is fond of saying, "God is good...all the time."

And so, God bless, and have a Happy Thanksgiving!


    0 of 8192 characters used
    Post Comment

    • lucybell21 profile image

      Bonny OBrien 

      7 years ago from Troy, N.Y.

      It's nice to know it's not all the turkeys fault.

    • pharmacist profile imageAUTHOR

      Jason Poquette 

      7 years ago from Whitinsville, MA


      Thanks for the encouragement. Well, I'm sure you come off as the smarty-pants anyway, but this will just be a little more fuel for the fire. :) Best wishes!

    • Sally's Trove profile image


      7 years ago from Southeastern Pennsylvania

      So cool! Now I get to be a smarty-pants next year when family members doze off after dinner blaming the turkey. Thanks for this unique look at Thanksgiving dinner. Voted up and everything else.

    • Pikachusif profile image


      7 years ago from Castelia City, Unova

      Yum yum yum! I always knew that science was both interesting and simultaneously delicious.

    • pharmacist profile imageAUTHOR

      Jason Poquette 

      7 years ago from Whitinsville, MA

      @Melissa-Chavez - Thanks for reading...and keep an eye on that blood pressure :)

      @Maren - Such kind words, thank you so much!

    • Maren Morgan M-T profile image

      Maren Elizabeth Morgan 

      7 years ago from Pennsylvania

      Wow - your writing tone is so perky and bright, while also being extremely informative. Voted up and more!

    • Melissa-Chavez profile image


      7 years ago from Pacoima,CA

      Very informative i never thought about it this way. I have high blood pressure so i will definitely be eating more cranberry sauce lol Thank you.


    This website uses cookies

    As a user in the EEA, your approval is needed on a few things. To provide a better website experience, uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

    For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at:

    Show Details
    HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
    LoginThis is necessary to sign in to the HubPages Service.
    Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
    AkismetThis is used to detect comment spam. (Privacy Policy)
    HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
    HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
    Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
    CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
    Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the or domains, for performance and efficiency reasons. (Privacy Policy)
    Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
    Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
    Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
    Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
    Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
    VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
    PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
    Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
    MavenThis supports the Maven widget and search functionality. (Privacy Policy)
    Google AdSenseThis is an ad network. (Privacy Policy)
    Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
    Index ExchangeThis is an ad network. (Privacy Policy)
    SovrnThis is an ad network. (Privacy Policy)
    Facebook AdsThis is an ad network. (Privacy Policy)
    Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
    AppNexusThis is an ad network. (Privacy Policy)
    OpenxThis is an ad network. (Privacy Policy)
    Rubicon ProjectThis is an ad network. (Privacy Policy)
    TripleLiftThis is an ad network. (Privacy Policy)
    Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
    Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
    Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
    Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
    ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
    Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)