I'm really into zombies right now, so I was psyched when I heard that World War Z was being made into a movie. However, I was disappointed, because I would have rather seen Patient Zero made into the next great zombie movie.
WWZ is more like a documentary that follows up on the aftermath of a zombie apocalypse, so that is the new hook to this particular story.
Patient Zero has a much more interesting hook in my mind, because they base it on science that is currently in use, which makes the potential for a zombie apocalypse more plausible in my mind. Patient Zero is the person whose brain has been manipulated through gene technology to become a zombie. Middle eastern terrorists design this technology and send Patient Zero to the United States to infect the rest of the nation.
Not sure who would play some of the characters, but I would like to see some middle eastern people play the middle eastern characters.