I start in one corner and concentrate on that small area only. If I have to take something to the garbage or another room, as I am leaving the room I try to find something in the rest of the room with the same destination and take it with me.
I wipe down furniture that needs it and do a rough vacuum in that area. I don't finish the dusting or vacuuming until I am finished with the entire room.
When I am finished the area I have designated for cleaning, I reward myself with coffee, time on the computer, time with my pets, whatever I want.
Then I move on to the next similar-size area in the job. Before I know it, it's all done because I have attacked the job in many small bites rather than one huge bite that would probably choke me.