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Some Facts About GLUTATHIONE : A Powerful Antioxidant

Updated on April 6, 2008


Glutathione is ubiquitous in living systems. It plays a vital role in maintaining cellular health that its depletion within a cell leads to the death of the cell. Its basic components are the three amino acids : L - glutamine, L- cysteine and glycine. It exists abundantly throughout the body. It's highest concentration can be found in the liver while it's least concentration is found in plasma. Glutathione is a very powerful antioxidant.


***Glutathione protects cells by suppressing some dangerous forms of free radicals.

***Its antioxidant power extends to DNA protection against reactions due to


***It protects the eyes and the skin against the damaging ultraviolet rays.

***It is the foundation of the p450 detoxification system that neutralizes toxins in the liver, kidneys, lungs and intestinal lining.

***Glutathione also plays vital role in the synthesis and repair of DNA, protein

synthesis, amino acid transport, and the synthesis of prostaglandin.

***It is also believed that it plays a role in enhancing the immune system.

The following contributes largely on the depletion of glutathione in the body :

Smoking, alcohol, caffeine, Tylenol and other drugs, vigorous exercise, ultraviolet radiation, air pollution, xenobiotics and other hormone-mimicking chemicals.

Glutathione levels are low in people who are suffering from severe ailments. Aging also leads to reduction in production of glutathione. Glutathione seemingly is the natural choice for the prevention of age-related diseases and it has been studied as a therapy for cancer, heart, disease and for slowing down the natural aging process.


The following are some of the highlights of the research on Glutathione:

* In one animal study, liver cancers induced by the toxic mold "aflatoxin"

regressed and survival was enhanced with glutathione admininistration.

* A study of women with ovarian cancer showed a reduced rate of side effects

and prolonged survival time when glutathione administered intravenously.

* Research published in the New England Journal of Medicine suggests that low glutathione levels may increase risk of heart attack.

* Glutathione concentration are correlated with the body's ability to fight viruses

including AIDS .

  • Inhalation of glutathione .shows some promise as a treatment to respiratory diseases.

The most reliable way to get glutathione into the circulation and into the cells is to take its precursors - the amino acids from which it is made. Cysteine in a form called N- acetylcysteine , appears to be the best option for this purpose.

Glutathione is not absorbed well when taken orally. Some researches made regarding this reveals that it is soaked up by the cells along the intestinal wall and remains there.





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    • proton66 profile image


      7 years ago from Southern California

      You are right. It is a very important enzyme. So, have you considered using Protandim which up-regulates one's natural glutathione by 300 percent? Just in case you want to try it, use this ID#226947.


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