For me, it would depend on a combination of A) how personal to me is the issue and B) the "tone" of the hub. Does it strike me the person is being combative and looking to spark a debate, or are they just stating their opinion?
For example, I'm a big fan of the second amendment, so if I stumbled across a hub where the auther was stating that not only shoud the second amendment be repealed, but that anyone who holds a contrary opinion is just a moron or a "hick", then yeah, I might have a thing or two to say about that.
On the other hand, if they're just stating their opinion without being rude or ignorant about it, or they're talking about something I have either no interest and/or knowledge about, I'll likely just move on as they are entitled to feel however they want.
There are far too many great hubs to read by too many great authors to get too hung up in negativity. (by the way... sorry my hub bothered you so much :p )