I'd go with sight. It would be the equivalent of walking around with your eyes closed. People can be hired to help you get around.
Not being able to smell would effect one being able to taste and not being able to (feel) the touch or embrace of a loved one would be heart breaking.
It also would be dangerous not to feel as one could be holding something that is extremely sharp, hot, or cold which is damaging their nerves and they wouldn't even know it. Walking around with broken bones or bad sprains would also harmful. Pain warns us.