I think I agree with Boogr, I would definitely vote for Jon Stewart. I think he is very intelligent, good willed, and if he presented a legitimate plan for his time in office I would support him.
However, I think Stewart running for office as an independent would have a profound effect on politics even though it is very unlikely he will actually be elected. Stewart would not be a democrat, nor a republican, but he would still have the support of millions of young adults who are often overlooked in politics. He has the potential to rock the bipartisan structure of US politics.
Frankly I just think it would be cool.