Clearly the answer is yes. However it really depends upon the couple and the contributing factors that may have led to the affair. One famous example is Bill & Hilary Clinton. I would imgaine it's probably easier when the whole world doesn't know what took place. Having said that everyone is entitled to have their own "deal breakers".
According to statistics the #1 reason for divorce is financial problems and adultery is cited only 25% of the time as the reason for getting divorced. I've also seen other studies that list "falling out of love" as being the #1 reason for divorce.
The following stats come from http://infidelityfacts.com/infidelity-statistics.h...
Percentage of marriages that last after an affair has been admitted to or discovered: 31%
Percentage of marriages where one or both spouses (admit) to infidelity, either physical or emotional: 41%
Percentage of men who say they would have an affair if they knew they would never get caught: 74%
Percentage of women who say they would have an affair if they knew they would never get caught: 68%
Apparently the majority of people who have cheated or fantasize about doing so don't end up getting a divorce because of it. One might also surmise that monogamy is very much like being on a strict diet for a lot of people.