A very complex question. Since I haven't a spouse I would view that question much differently from the personal perspective than someone married. My first thought is what does this question mean? Is it a broad question or is it specific and then to what?
Generally speaking, for me, is I try my hardest to remember we are people - human if you will, first. Gender follows. Gender is step two not step one. In the everyday interaction with women, I seek to see them as 'who' in meaning is this individual.
Doing this for awhile now, it has become easier to understand a woman I am interacting with. Deciding how to switch gears or shift my 'self' to continue the interaction can be tricky when human sexuality is tossed into the salad mix. Or, it may be as smooth as frozen, tart strawberry yogurt at mid-afternoon after classes. Then again, 'she' may make it as easy for me as a chatting while standing in line to get that comfortable cup of coffee before heading to work.
I guess what I am saying is if I was perceiving and sensing the setting of the interaction, yet was blind, that may tell a different story.
Geesh, did I wander about or what. Thanks for asking an intriguing question, algarveview.
Oh, I came back to edit for the second part of the question. Is it possible? Looking at your avatar I would say - yup, it is . . .