Absolutely. I stopped wearing makeup for a year when my ex was overseas. I'd always been a hit or miss when it comes to makeup - if I have time and feel like wearing it, I will, and otherwise I won't. I didn't especially notice a difference when I stopped wearing it altogether. But when he was getting ready to come back, and I started wearing it again, suddenly people seemed so much friendlier.
I started experimenting with it with my husband just to see, and he noticed that people strike up conversations more and smile more when I'm wearing makeup. When I'm not, I can get out, do my business, and come home without distractions, but if I've gotten made up, it will take longer and I'm likely to make new acquaintances.