Only time will tell.
We can only make predictions but we can't say for certain what is going to happen in 20, 50, 100 or even 1000 years time.
If we are wiped off the face of the earth by natural catastrophes such as floods, famine or 'locusts like insects', then earth will just probably be as barren as the other planets. New life might grow and thus continue the life cycle.
In Biblical terms, yes although we can't be sure what the Second Coming would be like so it would depend on our faith in God and His words.