The temporal lobe of the brain has been found to respond to some electrical stimulation by creating an exprience that seems to duplicate out of body experiences, near death experiences, feelings of euphorea, elation, and great peace as, sensations of precenses, and other feelings and sights that have been connected with metaphysical claims.
What does this mean?
It is not crushing proof that the metaphysical is not real - after all, it could simply show that the temporal lobe is the human gateway that allows these experiences; however, the physical properties of stimulation strongly suggests that the brain - specifically the temporal lobe - is reacting to stimulation without any metaphysical involvement.
The follows the understanding that dualism is probably inaccurate - that what we term the individual is a collection of neurons - we see this because physical damage to the brain in accidents cause changes to personality or even total loss of all personality traits.
Again, one may believe that the mind of the brain injured patients survives intact - but the evidence does not support that view.