My view is that Descartes got it all wrong. From a scientific perspective, every thought in the mind is also a neural pathway lighting up in the brain. Every feeling is a flow of hormones. Our posture affects our thinking, and breathing well increases our clarity of mind.
In Chinese medicine, each acupuncture point has several meanings: spiritual, mental, emotional, and physical. Each and every thought and feeling is related to the state of our bodies.
Buddhist practice teaches us to be aware of mind and body as one. I've done this for 30 years, and I can say, for me, Descartes was just wrong. The health of my spirit and the energy of my body are deeply interconnected. Yes, I can be in good spirits when the body is ill, and I can be bummed out when healthy. But the two are so deeply interconnected that I don't think of them as separate. I see how they all relate together.