The choices that we make in life lead us down different paths, and so long as we make the best of the paths that we chose, there is no need to change anything.
But I have always been curious as to what my life would have been like if I had never met that person, or decided on a different career, or ... the forks in the road are endless.
So, given a choice to live my life over, I would live it in a completely different way. And, at the end of that life if given the same choice, I would choose yet another way to live. How I wish I have a thousand lifetimes, so that I could explore all the possible nooks and crannies.