At the moment I will go with Anthony Joshua, as he has a good mix of skill, power, and comes into the fight in great shape. Deontay Wilder, I believe has more devastating one shot power, and comes in great shape. However, his overall skill level (boxing wise) is a bit below Joshua. There is a boxer by the name of Jarrell King Miller who is the most athletic "BIG" man I have ever seen in the ring. However, when I say BIG I mean BIG - hovering a ham sandwich below 300 lbs. If he could get down to 260, even 270 then I think he could give Wilder or Joshua a run for their money. I am leaving off Ortiz due to his last VADA test.