I have a personal profile on Facebook, with about 60 friends. I know most of them in person. A few are artists with whom I've done multiple collaborative projects online. A few are my cousins who I've never met. If I don't know someone well enough to have lunch with them, I don't accept their friend request.
I give most people who send me friend requests the link to my business page, where I have about 1,800 followers. Most people who try to friend me are interested in my artwork, anyway, and don't need to hear what I had for lunch, or about what my dogs are up to.