Popular Telugu actress Genelia D'Souza was born on August 5, 1987, in England. She is also known to people close to her as Harini. Her parents originally hail from Goa and later moved to England. Genelia made her move from England to India in pursuit of her childhood dream of becoming an actress. She got her first break in the movie 'Boys' directed by Shankar. The film was a box-office hit and soon Genelia started getting more roles. Genelia has so far acted in over a dozen Telugu, Tamil and Hindi movies.

D'Souza made her debut in Bollywood in 2003. Her first Hindi film was Tujhe Meri Kasam opposite Ritesh Deshmukh.^[3] She left Bollywood for a while to concentrate on the Tollywood Telugu industry. She first hit the lime-light with a Parker Pen commercial with Amitabh Bachchan^[8] and further did a Fair and Lovely 2003 Cricket World Cup ad with Krishnamachari Srikkanth. She was also a part of Mani Ratnam's stage show, Netru, Indru, Naalai.^[9] The Tamil director, Shankar, was very much impressed with her performance in both the ads and cast her in a leading role in his Tamil film Boys in 2003.

She made her Telugu debut with Satyam and went on to act in several superhits which made her hugely popular in south India. She acted in several successful telugu films like Happy, Samba and Sye. She followed it up with a pairing with actor Venkatesh in Subhash Chandra Bose which met with disappointment at the box-office.

Her second Hindi movie was Masti and was also opposite Ritesh. This film was a moderate success.

She played the role of Haasini in the Telugu blockbuster, Bommarillu, which also starred Siddharth Narayan in the lead. This movie was one of the biggest hits in her career and earned her critical acclaim and wide recognition. She won the Filmfare Award as the Best Actress for her performance, besides other awards. Her character of Haasini earned rave reviewes and this made her the favourite choice for that role in the remakes of Bommarillu in other languages. It was remade in Tamil as Santhosh Subramaniam in which Genelia was cast as heroine again. The film also turned out to be a rather successful as its predecessor. Her debut film in Kannada Satya In Love grossed 4 crores in its opening week thus setting a new record in the Kannada film industry.

She once again appeared in Bollywood in Mere Baap Pehle Aap alongside Akshaye Khanna, which was moderately successful. Her final breakthrough in Bollywood was through the blockbuster, Jaane Tu Ya Jaane Na, where she is the heroine in the role of Aditi Mahant aka "Meow". Her role has been widely admired for her sweetness and freshness, and new style of acting. The movie has debutant Imran Khan, Aamir Khan's nephew, as the hero. The movie released on July 4, 2008 and was a success across India and overseas.^[10] Her career in south india also continues with she reigning as a successful star in Telugu film industry. Her latest Telugu film Ready in which she was paired opposite Ram was a super hit. Her next film It's My Life, which is again a remake of Bomarillu with Harman Baweja is to be released in 2009. She will also act in David Dhawan's next film which is called Hook Ya Crook opposite John Abraham and Shreyas Talpade for the first time which is a cricket film, the film will be released in 2009. She also has the other film on her hand which is to released by mid of 2009 which is titled Life Partner with Tusshar Kapoor. She is now the brand ambassador of the new Fanta replacing Rani Mukherjee. She is also now the brand ambassador of chocolate Perk replacing bubbly Preity Zinta.