My answer may depend upon how each of us defines "artistic", but Raymond Massey, Lorne Greene, Raymond Burr and William Shatner were or are all fine actors of Canadian heritage that come to mind. I'm sure I have missed some obvious names.
What about Justin Beiber, Christopher Plummer, William Hutt and Cynthia Dale. Yes Justin Beiber's favourite restaurant is the one I work in. He was born in my hometown of Stratford, Ontario, Canada...eh?