ArtsAutosBooksBusinessEducationEntertainmentFamilyFashionFoodGamesGenderHealthHolidaysHomeHubPagesPersonal FinancePetsPoliticsReligionSportsTechnologyTravel

Gilenya: Help With MS Fatigue

Updated on March 7, 2019
Jen's Solitude profile image

I've been living with MS for 25+ years and have tried almost every medication available. I have also been evaluated and tested extensively.

Details of My Gilenya Failure

I began relating my Gilenya experience in August 2011, and 2012. I have roughly five months of information to share.

Symptoms to Report

As forewarned by Novartis, I experienced "eye-sight problems" especially during the third, fourth and fifth month on Gilenya. I can best describe my eye-sight changes as quite attention grabbing. Slowly I noticed an increased blurriness when reading printed material on information off of my computer screen. I also saw dark circles in the middle of my field of vision that I knew were not really there. Although I immediately suspected it was the fingolimod, I couldn't say for a certainty because I always suffer minor eye problems as a regular part of my life living with MS. Yet another problem arose while driving in a car. There was quite a difference in the road signs and being able to read them clearly. I came to the conclusion that I had to voluntarily limit my driving to the open highway. Reading highway signs was much easier than reading street signs. So the few times I drive these days I limit myself to well-known near-by areas or the highways that have bigger print on the road signs.

This is just typical MS vision symptoms, or macular edema caused by the fingolimod, or perhaps a case of ON (optic neuritis).


Not so glamorous is the next symptom I have experienced. Although not currently a problem diarrhea did occur infrequently the first three months of my Gilenya use.

Improvement in Enery Level-Decrease in Prozac Use

The best news I have to report since beginning Gilenya is in my energy level. My fatigue has actually lessened and I am so happy to feel myself getting stronger and stronger. So improved is my fatigue that I have even reduced the Prozac I was taking to get myself going. I look forward to discontinuing the Prozac altogether as my energy levels out and holds its current course.


Infections are a potential result of fingolimod and no one with MS wants to make him or herself open to getting the flu or increasing the seriousness of an infection. So far I have not had this problem. I fear the one area I may be most prone is my sinuses. I have noticed increased sinus problems and accompanying headaches, but so far no sinus infection.

Ongoing Examinations are Necessary

Liver enzymes are of great importance and I will need a complete blood work-up to see how my other physical problems are being helped or hurt by adding Gilenya to the mix.

Weighing the side effects with increased energy levels are a never ending consideration. It is natural to want to function at as high a level as possible. Yet other health concerns should not be ignored.

Eye sight cannot be tossed aside in favor of increased energy. Other problems such as liver enzymes are also crucial to good health. Gilenya usage means constant monitoring has to take place. Sound judgment must be used.

Discontinued Usage

Sadly, it was necessary to discontinue the drug. I was thrilled with the increased energy I received, but saddened with the severe reaction to my vision. Immediately after stoppage, my eye sight cleared up. Why ocular edema or swelling occurred in my case is unknown. It is a known complication that is well outlined by the drug manufacturers.

Some drugs work out and some drugs fail. No one knows what will happen until they personally try a drug for themselves. If a drug trial is unsuccessful, people with MS can patiently wait for the next drug coming down the pipeline.


This website uses cookies

As a user in the EEA, your approval is needed on a few things. To provide a better website experience, uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at:

Show Details
HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
LoginThis is necessary to sign in to the HubPages Service.
Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
AkismetThis is used to detect comment spam. (Privacy Policy)
HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the or domains, for performance and efficiency reasons. (Privacy Policy)
Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
MavenThis supports the Maven widget and search functionality. (Privacy Policy)
Google AdSenseThis is an ad network. (Privacy Policy)
Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
Index ExchangeThis is an ad network. (Privacy Policy)
SovrnThis is an ad network. (Privacy Policy)
Facebook AdsThis is an ad network. (Privacy Policy)
Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
AppNexusThis is an ad network. (Privacy Policy)
OpenxThis is an ad network. (Privacy Policy)
Rubicon ProjectThis is an ad network. (Privacy Policy)
TripleLiftThis is an ad network. (Privacy Policy)
Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)
ClickscoThis is a data management platform studying reader behavior (Privacy Policy)