ArtsAutosBooksBusinessEducationEntertainmentFamilyFashionFoodGamesGenderHealthHolidaysHomeHubPagesPersonal FinancePetsPoliticsReligionSportsTechnologyTravel

Arginine Alpha-Ketoglutarate - First Supplement Usage

Updated on February 26, 2014

<< Part 1 - What Is It? <<

Now that you’ve figured out what arginine alpha-ketoglutarate is you might be curious about the history of this supplement.

How was it discovered?

What would cause someone to want to start supplementing with arginine or increasing their intake through foods?

Let’s find out…

History of Arginine

The history of arginine actually starts way back in 1886 when a Swiss chemist named Ernst Schultze isolated it from a lupine seedling extract.

Not much of interest came of that discovery until 1932, when scientists at the University of Freiburg im Breisgau in Germany discovered the urea cycle.

This series of cellular reactions occurs in our bodies when ammonia is converted into a less toxic substance called urea. We then excrete urea out of our bodies when we urinate.

Ernst Schultze first isolated arginine in an extract made from lupine flowers like these, way back in 1886.
Ernst Schultze first isolated arginine in an extract made from lupine flowers like these, way back in 1886.

Arginine was found to have a significant role in the creation of urea, which shows that it’s needed to help detoxify our bodies.

Seven years passed and arginine was found to have another important role. In 1939, it was proven that arginine aided in the creation of creatine. I’m sure that many of you know what the benefits of having creatine in our bodies are. This shows that arginine can also help us perform better in the gym and recover faster by ensuring our bodies are rich with creatine.

1998 was another notable year for arginine. It was in this year that the Nobel Prize was awarded to three American scientists who discovered that arginine also aids in the creation of nitric oxide. Nitric oxide helps our veins relax and puts less stress on our hearts because our blood can flow easier. Better blood flow can also boost your performance in the gym.

Also in this year, a group of Italian scientists discovered that arginine helped reduce blood pressure in their patients.

Arginine started to appear so beneficial that doctors would take it and then end up recommending that their patients take it. Hospitals were even giving it to their patients so that their infectious wounds would heal quicker.

It was in the 1990s when the surge of arginine products started hitting the market. This is when you would have first started to see a lot of nitric oxide supplements come out.

Later it was found that when you combine arginine with alpha-ketoglutarate it ensures that the arginine is more easily absorbed. With this more efficient version or arginine you won’t have to use as much of it and you’ll get “more bang for your buck”. It’s usually listed as AAKG on supplement labels.

It’s funny that arginine was first found in a pretty flowering plant, was found to have all these health benefits and then is mostly used by big manly men trying to look ripped. I find it ironic that one source of some bodybuilders’ manliness sprouted from an extract from a flower!

All joking aside, arginine does seem to be a very beneficial amino acid with a well documented history.

Although we’ve gone over a few benefits of arginine already, let’s dig a little deeper and find out more about how arginine can benefit you.

>> Continue Reading Part 3 - Why Should You Take It? >>

When Did YOU First Start Using Arginine Alpha-Ketoglutarate?

    0 of 8192 characters used
    Post Comment

    • Bendo13 profile imageAUTHOR

      Ben Guinter 

      8 years ago from Colorado Springs, Colorado

      Yeah Hulk, there are a lot of benefits to supplementing with arginine for sure... Glad to hear that it helps you out in the gym!

    • profile image

      Hulk R 

      8 years ago

      Arginine seems to enhance muscle tone a little bit.

      I take it as part if the Max Powers 'Anabolic Stack' and it Definite increases power when combined with those other ingredients in the stack. it is extremely obvious that it does relax blood vessels because my.. um.. thing.. becomes more vascular consistantally when taking this product. I googled this effect and found out than many male enhancement products contain around 2000 mg of L- arginine a day.

      Other facts

      -It is believed to increase levels of HGH or human growth hormone

      -help make more nitric oxide which relaxes blood vessels.

      +this may also help men sexually

      -supports protein synthesis as it is involved in the transport and storage of nitrogen

      -Never use after a heart attack

      +A study was conducted on taking this product after a heart attack and 6 people died. None of the placebo group died.

      I wouldnt just take arginine by itself - definite take it as part if the stack - my favorite is the Dr Max Powers anabolic stack - been using it for 3 years now.....

    • Hello, hello, profile image

      Hello, hello, 

      8 years ago from London, UK

      Thank you for another great explanation about this product.

    working

    This website uses cookies

    As a user in the EEA, your approval is needed on a few things. To provide a better website experience, hubpages.com uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

    For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at: https://hubpages.com/privacy-policy#gdpr

    Show Details
    Necessary
    HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
    LoginThis is necessary to sign in to the HubPages Service.
    Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
    AkismetThis is used to detect comment spam. (Privacy Policy)
    HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
    HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
    Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
    CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
    Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the googleapis.com or gstatic.com domains, for performance and efficiency reasons. (Privacy Policy)
    Features
    Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
    Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
    Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
    Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
    Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
    VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
    PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
    Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
    MavenThis supports the Maven widget and search functionality. (Privacy Policy)
    Marketing
    Google AdSenseThis is an ad network. (Privacy Policy)
    Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
    Index ExchangeThis is an ad network. (Privacy Policy)
    SovrnThis is an ad network. (Privacy Policy)
    Facebook AdsThis is an ad network. (Privacy Policy)
    Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
    AppNexusThis is an ad network. (Privacy Policy)
    OpenxThis is an ad network. (Privacy Policy)
    Rubicon ProjectThis is an ad network. (Privacy Policy)
    TripleLiftThis is an ad network. (Privacy Policy)
    Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
    Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
    Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
    Statistics
    Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
    ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
    Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)