ArtsAutosBooksBusinessEducationEntertainmentFamilyFashionFoodGamesGenderHealthHolidaysHomeHubPagesPersonal FinancePetsPoliticsReligionSportsTechnologyTravel

Key Information About Atherosclerosis

Updated on May 10, 2024
srirad0675 profile image

Srikanth strongly believes that prevention is better than cure. He is of the opinion that awareness is a key to prevent diseases.

Narrowing of Arteries

Atherosclerosis is the narrowing of arteries because of plaque buildup. Plaque is usually made up of cholesterol, fatty substances, cellular waste products, calcium and fibrin.

Progressive Disease

Atherosclerosis is a slow, progressive disease that may start as early as childhood. However, it can progress rapidly.

Atherosclerosis

Wikimedia Commons
Wikimedia Commons | Source

Causes

Hypertension, obesity, inflammation due to conditions like lupus, and high cholesterol levels are known to cause atherosclerosis.

A new study in experimental mice indicates that a high-fat diet causes atherosclerosis.

This study by researchers from Tokyo Medical and Dental University (TMDU) was published in July 2021 in JACC Basic To Translational Science.

A study conducted in Sweden found that about 42 percent of the participants without known heart disease or symptoms had fatty deposits in the arteries of their heart, which experts call atherosclerosis.

In June 2022, research scientists in a study published in BMC Cardiovascular Disorders showed an independent association between triglyceride glucose index and subclinical atherosclerosis in healthy adults.

A unique Mount Sinai study (conducted in July 2022) focused on a multi-ethnic, underserved community in New York City, indicated that young Black adults are twice as likely to have atherosclerosis as similarly situated young Hispanic adults.

Younger women with previous preeclampsia are at a slightly higher risk of coronary atherosclerosis compared with women in the general population, states a study conducted in August 2022 in the Journal of the American College of Cardiology.

In January 2023, a team at the Centro Nacional de Investigaciones Cardiovasculares, working in collaboration with institutes in the United States of America, demonstrated that acquired mutations in the gene encoding the protein p53 contribute to the development of atherosclerotic cardiovascular disease.

During a research study conducted at Leiden University in February 2023, a combination of two sequencing techniques unveiled features of a subpopulation of cells that could be producing plaques in atherosclerosis. This process is associated with an autoimmune component driven by CD4+ T cells.

Animal studies fairly consistently show that higher protein diets are associated with more atherosclerosis. And some, but by no means all, epidemiologic studies in humans also show a link between protein intake and heart disease.

Obesity May Cause Atherosclerosis

Source

Symptoms

Pain in the upper body, shortness of breath, pressure in the upper body, and irregular heartbeat are some symptoms of atherosclerosis.

UMC

A research study conducted in July 2022 by Rabia Akilli and her team determined that UMC is a standalone predictor of atherosclerosis risk. Findings of this study were published in Menopause.

Diagnosis

Diagnosis is based upon a physical examination, ECG, and exercise stress test, among others.

Aorta-CAD

In December 2022, FDA granted 510(k) clearance to Aorta-CAD (Imagen Technologies), a cloud-based software device which employs deep learning capabilities to help detect aortic atherosclerosis and aortic ectasia on chest X-rays.

Imagen Technologies said the computer-assisted detection device creates annotations that alert doctors to findings on chest X-rays that may be indicative of atherosclerosis.

A clinical trial of the Aorta-CAD device revealed a 35 percent reduction of missed diagnoses for dilated aorta, a finding that suggests aortic ectasia, and a 62 percent reduction of missed diagnoses for aortic calcification, which can be associated with aortic atherosclerosis, according to Imagen Technologies.

“Aorta-CAD assists the physician to have a consistent and repeatable process to look into the cardiac silhouette providing additional information to enhance the patient’s treatment plans and care,” noted Scott Howell, chief medical officer for Imagen Technologies.

Treatment

Statins

Cholesterol-lowering statins keep atherosclerosis from getting worse. They pull cholesterol out of artery-clogging plaque.

Antiplatelet Medicine

An antiplatelet medication such as aspirin or clopidogrel (Plavix) may be prescribed to reduce the risk of heart attack and stroke.

"Carotid endarterectomy and carotid artery stenting are the main methods for treatment of carotid artery stenosis. Changes of postoperative vascular structure and fluid mechanics are important for restenosis, so determining how to minimize risk factors of postoperative flow is important for improving the therapeutic effect," said Zhiyong Song, University of Science and Technology, Beijing.

It is well established that natto intake is inversely correlated with cardiovascular disease mortality in Japanese adults. In addition, nattokinase, the primary active enzyme in natto, has been shown to inhibit the progression of atherosclerosis. Thus, it is unequivocal that natto has anti-atherosclerotic effects.

Meditation Reduces the Risk of Atherosclerosis

Prevention

Tobacco

Do not use tobacco products. Do yoga daily. Asanas (postures) like Parsva Sukhasana (easy side stretch) keep the arteries healthy.

Meditation

Meditate to beat stress. Get regular checkups. Have your healthcare provider check your blood pressure and cholesterol.

Results of research headed by a team at Albert Einstein College of Medicine suggest that revving up a cellular housekeeping process that slows down as we age may protect against atherosclerosis.

In March 2022, Ana Maria Cuervo, MD, PhD, and colleagues successfully minimized artery-narrowing plaque in mice that would otherwise develop those lesions, by boosting chaperone-mediated autophagy.

Do you practice yoga?

See results

Prognosis

Atherosclerosis cannot be reversed once it has occurred. However, lifestyle changes and treatment of high cholesterol levels slow the process from becoming worse.

Stopping smoking, following a healthy diet, managing cholesterol and staying physically active all decrease the risk of atherosclerosis and improve your overall health.

— Dr Laura M Drudi

Role of T Cells

In a research study, scientists at the La Jolla Institute for Immunology show that certain T lymphocytes that start out trying to fight the disease can end up increasing inflammation and making atherosclerosis cases even worse.

This content is accurate and true to the best of the author’s knowledge and does not substitute for diagnosis, prognosis, treatment, prescription, and/or dietary advice from a licensed health professional. Drugs, supplements, and natural remedies may have dangerous side effects. If pregnant or nursing, consult with a qualified provider on an individual basis. Seek immediate help if you are experiencing a medical emergency.

© 2020 Srikanth R

working

This website uses cookies

As a user in the EEA, your approval is needed on a few things. To provide a better website experience, hubpages.com uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at: https://corp.maven.io/privacy-policy

Show Details
Necessary
HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
LoginThis is necessary to sign in to the HubPages Service.
Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
AkismetThis is used to detect comment spam. (Privacy Policy)
HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the googleapis.com or gstatic.com domains, for performance and efficiency reasons. (Privacy Policy)
Features
Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
MavenThis supports the Maven widget and search functionality. (Privacy Policy)
Marketing
Google AdSenseThis is an ad network. (Privacy Policy)
Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
Index ExchangeThis is an ad network. (Privacy Policy)
SovrnThis is an ad network. (Privacy Policy)
Facebook AdsThis is an ad network. (Privacy Policy)
Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
AppNexusThis is an ad network. (Privacy Policy)
OpenxThis is an ad network. (Privacy Policy)
Rubicon ProjectThis is an ad network. (Privacy Policy)
TripleLiftThis is an ad network. (Privacy Policy)
Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
Statistics
Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)
ClickscoThis is a data management platform studying reader behavior (Privacy Policy)