ArtsAutosBooksBusinessEducationEntertainmentFamilyFashionFoodGamesGenderHealthHolidaysHomeHubPagesPersonal FinancePetsPoliticsReligionSportsTechnologyTravel

What Causes Hyperuricemia?

Updated on May 25, 2016
Fat women walking in the street.
Fat women walking in the street.


The human body needs to maintain a proper balance of everything, because too much or too low of anything can result to diseases. One of the examples of body imbalance is hyperuricemia. It is a condition wherein the amount of uric acid in the blood becomes abnormally high, exceeding the appropriate range of 2.4-6.0 mg/dL for women, and 3.4-7.0 mg/dL for men.

Uric Acid

Uric Acid is a metabolic waste product created from the breakdown of purines. Purine is a nitrogenous compound produced through cell turnover, or cell death, and is an extremely important component of a nucleoside, which combines with either deoxyribose, or ribose, and becoming a building block of DNA or RNA.

Additionally, purines, which could either be adenosine and guanine, are crucial in energy production and acceleration of many biochemical processes needed by the body. The role of purine-containing molecules in survival meant that the body has to rapidly and efficiently synthesize sufficient amount of purine using materials found in the body such as glucose, as well as a purine-rich diet.

Too Much Purine

Unfortunately, the mass producing of purine results to an excess or a surplus of purine and must be removed from the body. However, humans lack the necessary enzyme to break this down into a completely soluble material, and could only downgrade it as a uric acid.

On the other hand, uric acid is not entirely bad for the body, it just needed to be balanced, as it serves as an anti-oxidant, neutralizing the free-radicals, or pollutants that the body receives from the surrounding.

The Causes

Hyperuricemia then happens due to two primary reasons:

  1. When the level of uric acid in the bloodstream becomes too high because of huge amount of purine synthesized by the body itself or purine coming from the food consumed.
  2. All of the purine degraded into uric acid is not being excreted fast enough, or perhaps not at all, by the kidney through urine.

The secondary reasons are as follows:

  1. Medications, especially during chemotherapy, where there is an increase cell death, resulting in mass production of purine.
  2. Excessive alcohol consumption
  3. Genes – hyperuricemia could be inherited, and the genetic material of the parents might be the reason why the person has high uric acid.
  4. Too much intake of fructose-rich food, or beverages like soft drinks
  5. Drugs that suppresses the immune system
  6. Excessive consumption of niacin, or commonly called as vitamin B-3
  7. Renal Failure — incapacity of the kidney to filter waste products from the bloodstream.
  8. Obesity – lack of balanced diet has lots of negative complications, including high uric acid.
  9. Purine-rich diet — this includes meat, organ meat, sardines, sweetbread, asparagus, and others.
  10. Starvation – increases the body’s synthesis of purine as it tries to replace the insufficient supply of purine-rich foods, and a low-calorie diet also induces hyperuricemia, while the kidney gets impaired due to lack of support that it could only get from food-intake.

It Is Not Gout!

Hyperuricemia, however, must not be confused with the inflammatory arthritis called gout, as is the common misconception. A person with hyperuricemia does not necessarily have a gout, but it certainly increases the risk of acquiring the said condition.

Although it usually does not have a symptom, having a gout is the most visible sign that a person may have hyperuricemia. Other related diseases, as a consequence of a high uric acid, are kidney failures, kidney stones, and cardiovascular diseases.


Without any efficient medicine yet, the best way to avoid, or to lower the level of uric acid in the body is a proper diet, consumption of ionized alkaline drinking water to neutralize the acidity of the body, and a regular trip to the doctor to monitor the body’s immunity and health.


    0 of 8192 characters used
    Post Comment
    • Evane profile imageAUTHOR

      The Filipina Digital Entrepreneur 

      2 years ago

      Hi lolly! Thank you. I am glad to hear that. :)

    • lollyj lm profile image

      Laurel Johnson 

      2 years ago from Washington KS

      Very helpful and well written, easy to understand.


    This website uses cookies

    As a user in the EEA, your approval is needed on a few things. To provide a better website experience, uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

    For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at:

    Show Details
    HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
    LoginThis is necessary to sign in to the HubPages Service.
    Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
    AkismetThis is used to detect comment spam. (Privacy Policy)
    HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
    HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
    Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
    CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
    Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the or domains, for performance and efficiency reasons. (Privacy Policy)
    Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
    Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
    Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
    Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
    Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
    VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
    PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
    Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
    MavenThis supports the Maven widget and search functionality. (Privacy Policy)
    Google AdSenseThis is an ad network. (Privacy Policy)
    Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
    Index ExchangeThis is an ad network. (Privacy Policy)
    SovrnThis is an ad network. (Privacy Policy)
    Facebook AdsThis is an ad network. (Privacy Policy)
    Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
    AppNexusThis is an ad network. (Privacy Policy)
    OpenxThis is an ad network. (Privacy Policy)
    Rubicon ProjectThis is an ad network. (Privacy Policy)
    TripleLiftThis is an ad network. (Privacy Policy)
    Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
    Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
    Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
    Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
    ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
    Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)