What is SAM-e?
SAM-e Dietary Supplement
SAM-e is a dietary supplement which is said to help in the treatment of osteoarthritis, depression and liver disease.
A substance which occurs naturally, SAM-e is produced mainly in the liver but can be found in every cell of the human body.
The dietary supplement pronounced Sammy, SAM-e is produced in a laboratory and made into a capsule that is taken by mouth.
SAM-e is said to work as a donor in the parts of the body where not enough SAM-e is being produced.
SAM-e is sold as a dietary supplement in the USA but is widely available as a prescription drug in some European countries such as Russia, Italy, and Germany.
SAM-e has not been approved by the Food and Drug Administration.
Arthritis and SAM-e
SAM-e For Osteoarthritis
Osteoarthritis is caused when cartilage from the joints such as the knee wear away which causes the bones on either side of the joint to rub together, this causes swelling pain and a reduction in mobility and it can occur in any part of the body where two bones are connected by cartilage.
SAM-e is said to help by rebuilding cartilage, reducing swelling, easing pain, reducing stiffness and increasing Mobility.
SAM-e is also said to help in the production of tendons and muscle fibres which also help to reduce the symptoms of osteoarthritis.
Osteoarthritis should always be treated by a medical professional and you should seek the advice of your doctor before taking the supplement.
Anti Depressants and SAM-e
SAM-e Supplement For Depression
There have been many studies carried out on SAM-e and its positive effect on people who suffer from depression, the studies compare the effects of SAM-e with a placebo or sugar pill and although results vary from each of the studies the average results show around forty percent of patients who took the supplement had a significant improvement compared to around fifteen percent of those on the placebo.
Although it is not known why SAM-e works for patients suffering depression it is thought that SAM-e produces neurotransmitters which help to curb depression.
Often anti depressants don't work on patients who suffer from depression but the studies have shown significant improvement in patients who take both SAM-e and antidepressants.
If you are suffering from depression and the anti depressants that you are taking don't seem to have any effect ask your doctors advice on using a SAM-e supplement.
Depression is a serious illness and sufferers should not self treat with SAM-e always consult your doctor before taking.
SAM-e For Liver Disease
SAM-e is also said to be effective in treating liver disease and in Europe it is used as a prescription drug for Chronic liver disease.
Research has shown that patients with liver disease and other liver disorders have abnormal methionine metabolism, which depletes SAM-e.
By giving the sufferer synthetic SAM-e this effect was reversed.
Liver disease is often caused by an excess of alcohol over a long period of time and there are very few effective treatments for the disorder. SAM-e according to studies reduced the need for patients to undergo a liver transplant and lowered the risk of death by thirty percent.
Although SAM-e is widely used in Europe on prescription for liver disease it is only available as a dietary supplement in the USA because of " Lack of research"
Liver Disease is a serious illness and sufferers should not self treat with SAM-e always consult your doctor before taking.
SAM-e Supplement Side Effects
Side Effects of SAM-e
Although Same is relatively safe to take a minority of users can suffer from side effects from taking it
gas, vomiting, diarrhea, constipation, dry mouth, headache, mild insomnia, anorexia, sweating, dizziness, and nervousness and It can make some people with depression feel anxious.
Do not use SAM-e if you have:
- Bipolar disorder, SAM-e can cause people with bipolar disorder to change from depression to mania.
- Parkinson’s disease, SAM-e might make Parkinson’s symptoms worse.
- If you are going into Surgery, SAM-e might affect the central nervous system. This could interfere with surgery. Stop taking SAM-e at least 2 weeks before a scheduled surgery.
- Pregnant or Breast Feeding the effects to the unborn baby or breast feeding baby's are unknown please consult your doctor or midwife before using.
Other uses for SAM-e
SAM-e is also said to be effective in the treatment of chronic lower back pain, dementia, Alzheimer's, multiple sclerosis, spinal cord injury, seizures, migraine headache, and lead poisoning.
SAM-e is also said to help in slowing down the aging process by reducing wrinkles and rejuvenating the skin. and it is also said to boost intelligence.
SAM-e is a dietary supplement and if you suffer with any of the ailments above you should always consult your doctor before taking the supplement. Reviews have been good about it as a product but there have also been reviews with negative feelings towards it.