ArtsAutosBooksBusinessEducationEntertainmentFamilyFashionFoodGamesGenderHealthHolidaysHomeHubPagesPersonal FinancePetsPoliticsReligionSportsTechnologyTravel

Gene Soup: the DNA Neighborhood Makes a Difference

Updated on November 4, 2011
dallas93444 profile image

Dallas W Thompson was born in Bakersfield, California to "Grapes of Wrath" descendants. First born son of three siblings of a preacher

Chromosomes Are Territorial in Nucleus

A simple cell. DNA is inside the chromosomes... Chromosomes are territorial and where they are located within the cell influences how the cell functions...
A simple cell. DNA is inside the chromosomes... Chromosomes are territorial and where they are located within the cell influences how the cell functions...
Exploding the above chromosome and looking at human DNA. We have 23 pairs. Males have the small "Y" chromosome and females have the "X" chromosome...
Exploding the above chromosome and looking at human DNA. We have 23 pairs. Males have the small "Y" chromosome and females have the "X" chromosome...

Where Chromosomes Live in Cell; Determines How Cell Funtions...

Chromosomes Group Together In Specific Areas of Our Cells

Location, location, location. The place where our genes are and move in our cells influences how they function, both in health and disease.

Chromosomes prefer specific positions in our cells. They are not randomly scattered in our cells. The chromosome "neighborhoods" reflects the functional state of each chromosome and the gene it carries (DNA is located inside chromosomes). The organization change as a cell's behavior changes and in disease.

Location of Gene Within Cell Nucleaus Provides Clues to Identify Normal, or Diseased Cell

Identifying the locations that genes occupy within the nucleus and seeing how these positions change under different conditions is providing clues to how normal cells function and how some diseases, including cancer begin...

Favored Neighborhoods

Chromosome locations are not always in the same place. They tend to occupy a preferred location inside the nucleus. These arrangements change during dvelopment and in disease. What neighborhood the chromosome lives in influences whether the gene it carries are turned on or off. Genes change their location when their activity changers.

Possible Tool for Cancer Detection

Genome Cell Biologist are still learning the rules about the activity of genes in different places inside the cell nucleus. Where chromnosomes are located plays a central role in so,e cancers. Which chromosomes combine to form cnacer=prompting is influenced by where the chromosomes are located in the nucleus.

By learning where chromosomes typically reside in the nucleus might present opportunities for cancer detection. The position of the genes can help indicate whether a cell is canerous. Gene position soon will become a powerful molecular tool for assisting doctors to diagnose cancer at a very early stage. Certain cancers arise when two or more chromosomes in a cell break (radiation or toxins), and then improperly attach to each other, forming an abnormal combination. Chromosomes near each other combine more often than ones that lie far apart.

Related Information:

http://hubpages.com/hub/DNA-Does-Not-Determine-Entire-Genetic-Fate

New Book Available: www eyeswideshutanenigma dot com or Enter . . . . . . . "Eyes Wide Shut: An Enigma" into Google Search Engine -- Buy Direct and Save $$$


Comments

    0 of 8192 characters used
    Post Comment

    • dallas93444 profile imageAUTHOR

      Dallas W Thompson 

      6 years ago from Bakersfield, CA

      Thanks!

    • profile image

      takoua 

      6 years ago

      i love that this is a great info

    • dallas93444 profile imageAUTHOR

      Dallas W Thompson 

      7 years ago from Bakersfield, CA

      Healing Touch,

      Thanks! It is a dynamic process....

    • Healing Touch profile image

      Laura Arne 

      7 years ago from Minnetonka, MN

      Wow, this is great info on geneology. Can't wait to read more.

    • dallas93444 profile imageAUTHOR

      Dallas W Thompson 

      7 years ago from Bakersfield, CA

      ImChemist,

      Always room for more discusion and information!

    • ImChemist profile image

      ImChemist 

      7 years ago

      Thanks for this great information i was plan to publish hub like this but i think I'm late!!

    • dallas93444 profile imageAUTHOR

      Dallas W Thompson 

      7 years ago from Bakersfield, CA

      jacobkuttyta, Thanks for the information. I will check it out! There appears to be a "common ancestor." Also, there appears to be a vast narrowing of the population sometime in the past (forget how long ago)...

    • jacobkuttyta profile image

      Siny J 

      7 years ago from Delhi, India

      I found one more site stating the same: http://www.cambridgedna.com/genealogy-dna-genetic-...

    • jacobkuttyta profile image

      Siny J 

      7 years ago from Delhi, India

      Please visit the link below for more details

      http://www.africaresource.com/rasta/sesostris-the-...

    • jacobkuttyta profile image

      Siny J 

      7 years ago from Delhi, India

      I read somewhere that 97% of DNA is same for people around the world. Also it was confirmed by scientists that as per the DNA study all the people on the earth are from one mother of Ethiopian origin.

      Thanks for the new information

    • dallas93444 profile imageAUTHOR

      Dallas W Thompson 

      7 years ago from Bakersfield, CA

      vocalcoach,

      Intelligence: Knowing when to stop, knowing a little (not a lot) about what you do not know, saying I do not know, admitting mistakes, learning from my past and most of all, acceptance...

      Thanks for the compliments.

      My heritage is from a proud, and honest stock... people who had/have a work ethics... who are resilient.

    • vocalcoach profile image

      Audrey Hunt 

      7 years ago from Idyllwild Ca.

      I enjoy reading your profile. I love "the grapes of wrath" period. The stories, films. What a courageous people! You must be proud to be from that kind of stock.

      I wish I had 5% of your intelligence. Would love more than 5%, but do not want to be greedy :). Great hub here.

      Thanks so much, dallas.

    • dallas93444 profile imageAUTHOR

      Dallas W Thompson 

      7 years ago from Bakersfield, CA

      Darlene Sabella,

      Yes, where the chromosomes are located within the cell...

      Environmental issues play a major impact upon those with cancers... Notwithstanding the hereidtary factors... I have had melanoma and various skin cancers. I was in the sun a lot as a "youngin."

      Thanks for the "trophies!"

    • Darlene Sabella profile image

      Darlene Sabella 

      7 years ago from Hello, my name is Toast and Jam, I live in the forest with my dog named Sam ...

      Hello my adorable smart friend, I am going to send this to my daughter, she has a rare cancer that is not in any living relatives in our family, a very serious cancer. So you are saying it is the location of this gene? Not so much a history in the family as much as where this gene is. Hey, that is interesting, Ilove your hubs, rate way up love & peace darski

    • dallas93444 profile imageAUTHOR

      Dallas W Thompson 

      7 years ago from Bakersfield, CA

      GusTheRedneck,

      Perhaps better than "no genes!" Weepy people like weeping willow trees...

    • GusTheRedneck profile image

      Gustave Kilthau 

      7 years ago from USA

      Howdy dallas - I learned swome years back that the long-faced, sad and weepy people have "blue genes."

      Gus :-)))

    working

    This website uses cookies

    As a user in the EEA, your approval is needed on a few things. To provide a better website experience, hubpages.com uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

    For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at: https://hubpages.com/privacy-policy#gdpr

    Show Details
    Necessary
    HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
    LoginThis is necessary to sign in to the HubPages Service.
    Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
    AkismetThis is used to detect comment spam. (Privacy Policy)
    HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
    HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
    Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
    CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
    Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the googleapis.com or gstatic.com domains, for performance and efficiency reasons. (Privacy Policy)
    Features
    Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
    Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
    Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
    Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
    Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
    VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
    PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
    Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
    MavenThis supports the Maven widget and search functionality. (Privacy Policy)
    Marketing
    Google AdSenseThis is an ad network. (Privacy Policy)
    Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
    Index ExchangeThis is an ad network. (Privacy Policy)
    SovrnThis is an ad network. (Privacy Policy)
    Facebook AdsThis is an ad network. (Privacy Policy)
    Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
    AppNexusThis is an ad network. (Privacy Policy)
    OpenxThis is an ad network. (Privacy Policy)
    Rubicon ProjectThis is an ad network. (Privacy Policy)
    TripleLiftThis is an ad network. (Privacy Policy)
    Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
    Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
    Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
    Statistics
    Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
    ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
    Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)