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The Life and Times of Testosterone

Updated on September 24, 2011

Do you remember when you were nineteen years old and the world was your oyster? Do you remember how firm and toned your body was? You were quite the ladie's man and the world knew it, especially the ladies (at least in your mind). Your sex drive was off the charts.
This is the purpose and joy of testosterone.

Somewhere along the way, this feeling of invincability and desirability has faded, your muscles have lost their solidity, your appetite for a sexual feast has waned into a desire for a snack. The young stud is no longer staring back at you from the mirror. In his place is a middle aged man, perhaps with a beer belly.
You are now experiencing life with lowered testosterone levels.

Since this hormone can influence so much of our being both physiologically and psychologically, it would probably be a good idea to take a look at how it is created in your body.

Even though testosterone is produced by the testicles, its story does not begin there. Actually,the pituitary gland recieves a signal of gonadotropin releasing hormone (GnRH) which is created in the hypothalamus and secretes follicle stimulating hormone (FSH) and Luteinizing Hormone, lutropin (LH) into the bloodstream. The testicles receive the LH and begin to synthesize pregnenolone from cholesterol, which in turn is converted to androstenedione. This androgen gets reduced to testosterone which is released back into the bloodstream.

The testicles also contain Sertoli cells which utilize testostrone in conjunction with follicle stimulating hormone (FSH) to produce mature sperm cells.

Once in the bloodstream, the newly produced testosterone is free to interact with any cell that has a receptor for it. It can be used by mucles, bones and organs to restore much of that 19 year old stud who once looked back at you from the mirror.


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