Easy answer...it hasn't been known to happen before if you're going with just holistic meds. You also have to look at the type of Hepatitis for just how urgent treatment should be, some cases can be lived with for years before anything really life-threatening happens. Some types of hepatitis are treated with a strict medicinal regimen only, but it has to be started and stuck to for the duration of the treatment, which is often about two years. However, know that untreated hepatitis is much more likely to cause any number of severe, potentially deadly side effects including hepatocellular carcinoma, which has a survival rate of about 6-12 months after diagnosis with treatment. Without treatment, the disease often runs its course in three months or less.