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Pharmacological Management of psychosis

Updated on June 22, 2016

Overview of the Major Developments in the Treatment of Psychosis Including Major Drug Classes

The drug therapy of Psychosis remains problematic despite its efficacy in many cases. Significant fractions of patients do not recover, and several others experience from unpleasant side effects. Over the years, psychosocial advances in the psychosis management have moved from a merely behavioral center to an emphasis on the relations of behavior and cognitions symptoms of psychosis. There has been a severe stress on the factors sustaining the experience of residual symptoms of psychosis for instance hallucination. Also, on the disturbance and distress, that can be linked with these symptoms

The CBT intervention by psychotic symptoms literature points out that there is a growing support body for a series of related CBT treatment programs. However, it comes into view that, there is a sturdy support in the structure of randomized managed trials for the exercise of individual CBT in treating importunate psychotic symptoms. This form of psychological therapy, has been shown to fabricate considerable improvements in symptomatological psychosis and pain linked with psychotic symptoms

Major Drug Classes and neurotransmitters involved in the drugs

On the other hand, atypical antipsychotics (newer), successfully cure psychotic symptoms, but have a lesser frequency of extra pyramidal side effects compared to conventional agents. These antipsychotics have effects on serotonin, dopamine, and histamine among others. Current atypical antipsychotics incorporate amisulpride, aripiprazole, and quetiapine among others

There are two major types of antipsychotics: Conventional or typical and atypical antipsychotics. The conventional antipsychotics are divided into several different classes according to their chemical structure: phenothiazine (example chlorpromazine), putyrophenones (example droperidol), thioxanthines (example flupenthixol), and diphenylbutylpiperidines (example pimozide). Conventional antipsychotics obstruct muscarinic, dopamine, and alpha-adrenergic histamine receptors

Severe Side Effects of Antipsychotic Medications and Potential Alternative Treatments Acute Dystonia

These symptoms generally occurs secondary to therapy by neuroleptic drugs. In general, the symptoms develop in minutes to days and frequently affect the trunk, face, hands or neck. The effects remain uncommon with the use of atypical antipsychotics. However, there are several types of dystonia, which incorporate laryngospasm, torticollis, retrocollis, opisthotonos, and oculogyric crisis. Since this is a serious medical condition, interventions demands urgent medical treatment and assessment, appropriate patient education, and ensuring that the effects are documented in clinical record


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