I really think that the Astros will finish with more than 110 losses but won't get to that record of the Mets. Houston however will be the worst team by far in MLB during the 2013 season. It's going to be a long year at the Juicebox.
So the Astros move to the AL West this season and have new uniforms and are going back to Orbit that green space creature for their mascot. I don't see how any of that is going to help them play better. It would be pretty tough to top the Mets though.
The Astros will definitely lose at least 100 games this year because they're now in one of the toughest divisions in MLB, the AL West, but they won't beat the Mets' record. Maybe they'll start to turn it around next year. Later!