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Dr Perricone Neuropeptide Facial Cream Reviews.. A New Era?

Updated on December 13, 2017

Some people think that a gloomy face requires contraction of a number of muscles more than that a person needs to smile, and whether this is true or not, people tried to erase wrinkles by affecting the nerves that control muscles in the face, using anything that can do that, including the extremely poisonous material - Botulinum Toxins.

It takes time to use a natural material occurring in the body to produce the same effect of a foreign material, that time is needed for understanding the role of so many biochemical materials present in the human body. This is what happened to Neuropeptides, is it a new era of facial creams that remove wrinkles? this is what we try to discover in this hub.

Botulinum Toxins ( Botox )

It is a neurotoxin produced by the anaerobic bacterium Clostridium botulinum which causes flaccid muscular paralysis seen in botulism, and is also the main paralytic agent in botox.

It acts as a neurotransmitter that modifies the nerve signals of the nerves supplying the muscles, so that it causes paralysis of the muscles and as a result they can not contract.

This is why Botulinum Toxins are used in cosmetics, as well as for overactive sweat glands, overactive bladder, twitches....etc., where muscles are required not to contract. It is needed to be injected every 6-9 months. Its most popular use is to treat wrinkles locally (at the site of wrinkles).

Its use involves considerable risks and the FDA notified the public that Botox and Botox Cosmetic (Botulinum toxin Type A) and Myobloc ( Botulinum toxin Type B) have been linked in some cases to adverse reactions including respiratory failure and death.

Good Botox

Bad Botox

Neuropeptides and the Skin

Neuropeptide occurs normally in the human body, their building units are amino acids ( the bricks that build proteins). They are released by the nerves to either transmit a signal, or modulate a nerve signal by causing other neurotransmitters to stop or start impulses.

Argireline (one of the neuropeptides) blocks the nerve signals that control the contraction of facial muscles, and this produces a significant reduction both in depth and intensity of contraction of facial muscles, and this is why it is applied to the skin to get temporary smoothing effect. Neuropeptides may cause the skin to increase collagen production.

Regular use of neuropeptides may affect the skin muscles in such a way that causes the skin to actually lose wrinkles that have already formed, they shrink and become less noticeable. They may increase production of collagen which holds the skin firmly from beneath, and this makes it looks smoother and finer.

The Most Popular Neuropeptide Cream

Searching the web, I found that Dr Perricone Neuropeptide Facial Contour Cream 2.5 oz is the most popular product out there - No, I am not an affiliate -.

I found 272 reviews of the cream on QVC, 57 percent of them would recommend it to a friend, and more than 46 % were fanatic about the cream, and about 30 % that did not find it appropriate for them.

- An example of the enthusiastic testimonials is as follows:


Overall Rating *****

Not only am I extremely happy with the results, but all my friends are telling me when they see me... what have you done? Your face/skin look absolutely fresh/young.....
Is the only cream I have seen results immediately!
I'am also using the Hi Potency am/pm - from Dr Perricone, as well as the eye cream!
These products are the best I've used and I have used the best out there in the market, but by far, -Dr Perricone's are #1
Love,love,love - can't be without it.

Would you recommend the product as a gift?

Who would this be a perfect gift for?

- An example of the "do-not-like" testimonials is as follows:

"Smell Awful

Overall Rating *
Did nothing for me and I used it for almost 3 weeks. It smells funny and it also burns just after putting it on. I did find like another comment said that if you put your moisturizer on after then the smell goes away.
Would you recommend this product as a gift?

It contains lecithin and Dimethicone which have good moisturizing properties, DMEA which does in fact tighten the skin and improves its texture,
Rice Bran and Germ oils which contain vitamins E and A, and an Oligopeptide (the neuropeptide), all are dispensed in inert materials and Parabens as preservatives. Read about the best ingredients for you skin

What amazes me is the fact that the manufacturer company did not do any thing to the cream odor which many customers did not like.

For the price, it may be considered from different perspectives, on the one hand it is very reasonable as an alternative to very expensive and risky treatments - and the manufacturers do not point to this -, on the other hand the cream is a bit expensive as a routine beauty care - and the manufacturers fixes this idea by making multiple payments for the price.

The conclusion?, it is of good value for those who are seeking an alternative for a highly expensive and risky treatment for wrinkles, and for the rest, it is good for those who can afford the price and give it a try.

Neuropeptides and the Future

Whether the present products are effective or not, the trend itself is very promising as it will be submitted to comprehensive and continued research.
Imagine that you use a cream in the morning to remove wrinkles,like you use the soap to clean your face!


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    • profile image

      Nancy Richards - Lose Wrinkles 7 years ago

      Thanks for the info! Great help!

    • profile image

      Janet Daniels 7 years ago

      I'm turning 35, and lines are starting to become visible. I seriously need help!