My most memorable vacation has to be to New Orleans during Mardi Gras when I was in college. It was a fly by the seat of our pants, live in the moment kind of trip. No plans, no reservations...just my college friend and I checking out the Big Easy.
Looking back it could have went completely a wrong in so many ways. But the residents of New Orleans took care of us and offered a southern hospitality like none I've ever experienced.