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Psychoactive Drugs: Physical Effects and Withdrawal Symptoms

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By Maddie Ruud



Psychoactive Drugs & Substance Abuse

Any substance that alters mood, thought, or perception is known in psychology as a psychoactive drug. More specifically, a drug is called a controlled substance when approved for medical use through prescription, or illicit if illegal. While many psychoactive drugs have pleasurable-- if not always beneficial --effects, substance abuse may develop if an individual continues to use after several incidents in which use has negatively affected his or her work, education, or social relationships.

Substance abuse occurs for two reasons: physical and psychological dependence. Physical dependence results from the body's defense mechanism against poisoning by developing drug tolerance over time, requiring higher doses of the substance to maintain the same effects. In addition, the neurological changes incurred as a result of drug use encourage the brain to cease production of important neurotransmitters necessary for functioning. Withdrawal symptoms are often crippling, as the body becomes unable to operate without the substance.

Equally as powerful can be the grips of psychological dependence. Cravings for the drug's pleasurable effects can be irresistible, and in combination with the physical discomfort from ceasing use, make recovery a painful prospect.

Classes of Psychoactive Drugs

Psychoactive drugs can be classed into three main categories: stimulants, depressants, and hallucinogens. The effects and withdrawal symptoms of popular drugs from each category can be found below.


Stimulants

Stimulants, also known as "uppers," speed up activity in the central nervous system, suppress appetite, and generally make a person more alert and energetic. They increase pulse rate, blood pressure, and respiration rate, and reduce blood flow to the brain. In high doses, stimulants make people nervous, jittery, and prevent sleep.

Caffeine

  • Effects- wakefulness, alertness, increased metabolism, slows reaction time
  • Withdrawal- headache, depression, fatigue

Nicotine

  • Effects- calm, alertness, lowered appetite, increased pulse rate and metabolism
  • Withdrawal- irritability, anxiety, restlessness, increased appetite

Amphetemines

  • Effects- increased metabolism, alertness, elevated mood, suppressed appetite
  • Withdrawal- fatigue, increased appetite, depression, excessive sleep, irritability, anxiety

Cocaine

  • Effects- euphoria, energy boost, excitement, suppressed appetite
  • Withdrawal- depression, fatigue, increased appetite, excessive sleep, irritability


Depressants

Depressants, or "downers," decrease activity in the central nervous system, slow down body functions, and reduce sensitivity. The cumulative sedative effects make taking combinations of depressants extremely dangerous.

Alcohol

  • Effects- lowers inhibitions, slows reaction time, impairs motor function, and perceptual ability
  • Withdrawal- tremors, nausea, sweating, depression, irritability, sometimes hallucinations

Barbituates

  • Effects- sleepiness, calm, sedation, decreased muscle tension, impaired coordination and reflexes
  • Withdrawal- insomnia, anxiety, sometimes seizures, lung collapse or heart attack

Tranquilizers

  • Effects- lowered anxiety, calm, sedation, decreased muscle tension
  • Withdrawal- restlessness, anxiety, irritability, muscle cramps, insomnia

Narcotics

  • Effects- pain relief, constipation
  • Withdrawal- nausea, diarrhea, cramps, insomnia


Hallucinogens

Hallucinogens, or "psychadelics," are drugs that distort perceptions of time and space, alter mood, and cause sensations not based in external reality. Hallucinogens often magnify whatever mood the user was in prior to use.

Marijuana

  • Effects- euphoria, relaxation, increased appetite, reduced ability to store new memories
  • Withdrawal- anxiety, insomnia, decreased appetite, hyperactivity

LSD

  • Effects- excitement, euphoria, hallucinations, experiences perceived as spiritual or profound
  • Withdrawal- confusion, disorientation, anxiety

Ecstasy (MDMA)

  • Effects- euphoria, lowered inhibitions, dehydration, sometimes dizziness, eye twitching
  • Withdrawal- depression, fatigue, sometimes suicidality

Comments

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Lela Davidson profile image

Lela Davidson  says:
2 years ago

Very comprehensive and informative! Thanks, Maddie!

barryrutherford profile image

barryrutherford  says:
2 years ago

do you have any info on ZOLOFT 50ml

Maddie Ruud profile image

Maddie Ruud  says:
2 years ago

Barry:

Any antidepressant medication should be tapered off under supervision of your doctor and/or psychiatrist. If you stop taking Zoloft all at once, withdrawal symptoms can range from lightheadedness, insomnia, and tremors, to anxiety, muscle pains, and nausea. These symptoms usually last 1-2 weeks, but can continue anywhere up to a month. You should always consult your doctor before you stop taking your medication.

Good luck,

Maddie

barryrutherford profile image

barryrutherford  says:
2 years ago

thanks maddie...I gues their regarded as uppers..althought they are called/do something else. If your read the script or mims you needs to be a shrink on brain surgeon to understand what they are doing

Maddie Ruud profile image

Maddie Ruud  says:
2 years ago

Barry:

Zoloft is an SSRI, or Selective Seratonin Reuptake Inhibitor. Seratonin is a neurotransmitter that functions in the relaying of messages between nerve cells in the brain, and is involved primarily in sleep, mood, and appetite. Hence, when there is a lack of seratonin in the brain, the symptoms of depression: excessive sleep or insomnia, appetite changes, and sadness. SSRIs keep the nerve cells from reabsorbing the seratonin they have released, meaning that more of it is available to pass on its message to the next neuron... thus (hopefully) correcting the lack of feelings of well-being and calm that a normally functioning brain experiences.

TJSUNCOAST  says:
2 years ago

First advice is to never take any "Pscho drugs" as I call them. The only results the have is bad ones.

ann  says:
10 months ago

Drugs are illegal

earnestshub profile image

earnestshub  says:
8 months ago

Hi Maddie. Margolis in his comprehensive book on drugs calls alcohol a dangerous fifth rate depressant yet it is not only legal but heavily promoted. The most dangerous drugs are legal prescription drugs. The number of deaths far exceed those for illegal drugs. All drugs are potentially dangerous and some of the warnings on prescription drugs are terrifying! So called side effects like death are common. If the FDA and the US Government continue to demonize recreational drugs, kids will keep taking them, the mafia will keep selling them, and no tests can be viable in such cases as the contents could be anything these soul-less bastards have a-plenty at the time. Although the Government goes on about drugs such as mda mmda GHB etc, and tells direct lies about the dangers of some drugs these drugs are nearly always something else. I applaud you for writing this hub and hope it is read by those who use drugs casually and without thought.

By the way government info on marijuana are a joke. These days your average ten year old knows enough to see through the fear campaigns, and the way stats are gathered do not take in to consideration those who self prescribe because they are pre-suffering the problems that some drugs are supposed to have caused.I have used MJ daily for 35 years now for chronic CNS pain and nothing comes near it for safety. If I had taken prescription drugs for pain I would have died twenty years ago from renal failure according to my doctor. All my doctors have been totally supportive of my use and I live a normal full life that would be unbearable without it.

Mighty Mom profile image

Mighty Mom  says:
8 months ago

Not sure what Margolis means by a "dangerous fifth rate depressant" (is that supposed to be some kind of pun -- get it, "fifth"??). Alcohol kills more people than all the other drugs combined. There is nothing "fifth rate" about it. But it definitely is dangerous. In fact, you should add "seizures" to the list of potential withdrawal symptoms from alcohol, too.

Great hub. I hope a lot of parents read it! MM

earnestshub profile image

earnestshub  says:
8 months ago

Hi Mighty mom, that was funny! I have not read Margolis for twenty years, but if I remember correctly By fifth rate I took him to mean that it has a very bad effect and there are many other depressants that are less dangerous to use with less likelihood of death.Your comment is spot on and seizures should be on the list.

sequoiablessed profile image

sequoiablessed  says:
4 months ago

Very well written article Maddie. It is concise and to the point, very informative. I can tell you are very well informed and I hope the message gets through. Drugs are dangerous no matter where you get them from and are to be used with great caution and forethought.

PB Smith  says:
5 weeks ago

Not a bad summation of the effects although your info on LSD is not really accurate. LSD,Psylocibin and other tryptamine type psychedelics produce tolerance very rapidly and thereby do not lend themselves to addictive abuse in the usual sense. There are also no withdrawal symptoms such as you speak of from LSD.

earnestshub I agree with 100%? :)

Education is key and not the propagation of lies designed to scare rather than teach.

PB Smith  says:
5 weeks ago

earnestshub the ? was a typo.

I agree and feel more accurate information is more effective at reducing drug abuse than this costly, corrupt and woefully ineffiecient war on drugs has been.

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