my current favorites are NCIS, House, and Bleach. The first two are because I love funny drama with a good helping of "smartness." The last is because I've always been a fan of animes and Bleach is really good at being interesting without boring. Bleach also does a great job of laughing at itself and anime cliches.
p.s. if you're a Hugh Laurie fan you should check out Blackadder. It was a really great british comedy series that ran for five seasons (i think) and Hugh was in from season 3 onward. He's much different from his House role, but is hilarious. plus, you get to hear his real accent, which is always awesome.