ArtsAutosBooksBusinessEducationEntertainmentFamilyFashionFoodGamesGenderHealthHolidaysHomeHubPagesPersonal FinancePetsPoliticsReligionSportsTechnologyTravel

Successfully Anticipating a MS Exacerbation or Flare-up

Updated on March 8, 2019

What are the symptoms of a MS flare-up? Is there any research providing MS treatments that will prevent a flare from occurring? How can you tell if you are about to have an exacerbation?

I find myself thinking about these questions a lot more than usual especially this past week or so, because I’m pretty sure my body thinks it is time for me to have a seasonal flare-up of some type.

Even though I have had MS long enough to know I can’t prevent the inevitable, there is still a piece of my reasoning mind that wants to believe I can will it away or loosen its grip by some sort of advanced mental planning.

I suppose that is based on the fact that sometimes, if everything goes just right, I have felt I have curbed an all out attack or lessened its affects by anticipating its arrival and forseeing trouble spots with my immune system.

In truth, I really don't know that I did anything to lessen or reduce an attack because there have been so many times when my best just wasn't good enough to prevent my body attacking itself. However on the chance that once in a while I can help my body not attack me, I try to do what I can to ward off an attack.

The best case scenario right now would be for me to endure a fatigue flare-up. No walk in the park, but something I am used to dealing with. I know for example, I can recover from a fatigue flare-up by confining myself to bed and being bored out of my mind by my inactive state.

As torturous as the mere thought of me being stuck in bed is, I know it is much better than the sidelining I would have to endure if an all out exacerbation were to occur.

Then we would be talking about the roller coaster ride that is a typical 3-day solu-medrol steroid pulse.

I would do anything to avoid that particular ride.

My Warning Signs

What, you may be wonder, has my attention piqued, my antennae raised, and warning bells sounding?

I’d say it is the swift return of a combination of killer fatigue and severe nerve pain. Being no stranger to either one of these symptoms, I think I have a fairly high threshold for both.

My Prozac experiment has been successful in relieving the fatigue that had made it impossible to do little more than care for my most basic daily functions.

My prescription of Lyrica has done more than I ever dreamed could be accomplished in controlling the burning nerve pain that exists in my right leg which has just recently quickly risen to an intolerable level.

So when my prescriptions suddenly stopped working effectively to keep the fatigue and pain in check, I knew something was not right in the vessel which houses my MS. Like the rivers and creeks that constantly overflowed their banks, this winter, the pain and fatigue was flooding my system and the barrier between stabilized health and relapsing MS was crumbling down.

I can feel my immune system developing small leaks like those sandbags that fail to hold back the rising flood waters when a river-bed crests. Once the first trickle begins you know the barrier will fall completely if the water keeps rising.

My trickle takes the form of pain and fatigue, if I can’t stabilize them with bed rest, then the flood will begin and a full-fledged attack- my immune system against itself- will commence.

Those Pesky White Lesions

Based on the previous damage identified by those pesky white lesions that are visible from MRI imaging, an approximation can be made of what part of the body has been damaged or is undergoing damage. We don’t want our lesions to be active we want them to be dark or inactive.

Inactive lesions mean there is damage but the lesion is healed or just not doing any more damage.

An active lesion suggests new deterioration.

Too many flare-ups, whether  in old or new locations of the body, could indicate a new lesion has formed or an inactive lesion has become active again. 

Fatigue and nerve pain in general are not new. However, I am experiencing more nerve pain in the same leg. Recently the pain has spread to the sole of my right foot which now means the entire leg has been invaded by the painful nerve monster. It is sad to finally have loss the sole of my right foot to this type of nerve pain, but I must say, my foot fought a valiant battle, lasting far longer than I thought possible.

As to its significance, I can only hope that right leg pain is right leg pain, adding the sole of the foot means nothing, as the damage still originates from the same place. So I would like to tell myself the pain in the sole of my foot is not indicative of any new lesion forming, as that is not usually how nerve pain is explained.

In and of itself, fatigue and nerve pain do not equal a MS exacerbation. That is the good news!

The Not So Good News

If the fatigue and nerve pain keep up at their current pace and in addition I began suffering leg weakness, well then I will no doubt be in trouble. That is the course I follow on the road to relapse-town. I’m hoping bed rest will prevent the expansion into leg weakness.

Arm Weakness

For at least 2 weeks now, I have been very aware of weakness in both my right and left biceps. This is new and totally has my undivided attention. This is the type of symptom that could be indicative of a new and active lesion and is in line with the natural course of relapsing/remitting MS that has been part of my life for 16 years now.

For those familiar with MS, the term MS Hug, is how I chose to describe the feeling in my biceps. It is as if a band has been wrapped around each bicep and is being pulled enough to gently squeeze my biceps. I can't really describe it as a painful sensation, sense it feels more uncomfortable than painful.

I will be very worried if my arm weakness increases, and my fatigue and nerve pain stay at their current high-level, and my leg weakness returns.

Then I have no doubt it is time to see my neurologist, as to this very day I find myself enjoying the ability to walk too much to wait for it to return without the aid of steroids. I have always been impatient that way.

Will the Other Shoe Drop?

Right now, I would say there is a 50/50 chance. I am definitely in alarm mode as I wait and hope I can figure out a way to keep the lid on and the sand bags in place. The next couple of weeks will tell for sure.

I thought others might appreciate reading about my process when I think I'm about to flare. What I try to determine, physically, and how I approach things mentally. If it helps you face your own impending flare-up or rule out a flare, then I will be happy I put these thoughts down in writing.

With both symptoms stabilized, I was truly enjoying my days of limited but steady activity. With winter nearing its end I was gleefully anticipating outdoor activity again. Soaking in the sun and watching my bird friends bathing themselves and eating from the feeders I planned to place in my backyard for the first time in two years, were just two of the outdoor activities I had in the works.

My preparations suddenly seem premature and arduous my two symptoms returning with a vengeance seemingly out of the blue, with a suddenness I can only liken to the turning on of a light switch.

It is deflating for sure, but since there is still a small chance that the other shoe won't drop, I will do what every other person with MS does in this situation, hurry up and wait! Followed by some hobbies to pass the time regaining my energy, one such being writing I suppose.

The Other Shoe Hasn't Dropped!

I am happy to update this with the good news that it seems a major flare-up is not in my immediate future. The weekend went better than expected and I am now feeling 96 percent sure that it was a fatigue flare-up and nothing more!

Excited and relieved would be two good words to describe how I am feeling now.


This website uses cookies

As a user in the EEA, your approval is needed on a few things. To provide a better website experience, uses cookies (and other similar technologies) and may collect, process, and share personal data. Please choose which areas of our service you consent to our doing so.

For more information on managing or withdrawing consents and how we handle data, visit our Privacy Policy at:

Show Details
HubPages Device IDThis is used to identify particular browsers or devices when the access the service, and is used for security reasons.
LoginThis is necessary to sign in to the HubPages Service.
Google RecaptchaThis is used to prevent bots and spam. (Privacy Policy)
AkismetThis is used to detect comment spam. (Privacy Policy)
HubPages Google AnalyticsThis is used to provide data on traffic to our website, all personally identifyable data is anonymized. (Privacy Policy)
HubPages Traffic PixelThis is used to collect data on traffic to articles and other pages on our site. Unless you are signed in to a HubPages account, all personally identifiable information is anonymized.
Amazon Web ServicesThis is a cloud services platform that we used to host our service. (Privacy Policy)
CloudflareThis is a cloud CDN service that we use to efficiently deliver files required for our service to operate such as javascript, cascading style sheets, images, and videos. (Privacy Policy)
Google Hosted LibrariesJavascript software libraries such as jQuery are loaded at endpoints on the or domains, for performance and efficiency reasons. (Privacy Policy)
Google Custom SearchThis is feature allows you to search the site. (Privacy Policy)
Google MapsSome articles have Google Maps embedded in them. (Privacy Policy)
Google ChartsThis is used to display charts and graphs on articles and the author center. (Privacy Policy)
Google AdSense Host APIThis service allows you to sign up for or associate a Google AdSense account with HubPages, so that you can earn money from ads on your articles. No data is shared unless you engage with this feature. (Privacy Policy)
Google YouTubeSome articles have YouTube videos embedded in them. (Privacy Policy)
VimeoSome articles have Vimeo videos embedded in them. (Privacy Policy)
PaypalThis is used for a registered author who enrolls in the HubPages Earnings program and requests to be paid via PayPal. No data is shared with Paypal unless you engage with this feature. (Privacy Policy)
Facebook LoginYou can use this to streamline signing up for, or signing in to your Hubpages account. No data is shared with Facebook unless you engage with this feature. (Privacy Policy)
MavenThis supports the Maven widget and search functionality. (Privacy Policy)
Google AdSenseThis is an ad network. (Privacy Policy)
Google DoubleClickGoogle provides ad serving technology and runs an ad network. (Privacy Policy)
Index ExchangeThis is an ad network. (Privacy Policy)
SovrnThis is an ad network. (Privacy Policy)
Facebook AdsThis is an ad network. (Privacy Policy)
Amazon Unified Ad MarketplaceThis is an ad network. (Privacy Policy)
AppNexusThis is an ad network. (Privacy Policy)
OpenxThis is an ad network. (Privacy Policy)
Rubicon ProjectThis is an ad network. (Privacy Policy)
TripleLiftThis is an ad network. (Privacy Policy)
Say MediaWe partner with Say Media to deliver ad campaigns on our sites. (Privacy Policy)
Remarketing PixelsWe may use remarketing pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to advertise the HubPages Service to people that have visited our sites.
Conversion Tracking PixelsWe may use conversion tracking pixels from advertising networks such as Google AdWords, Bing Ads, and Facebook in order to identify when an advertisement has successfully resulted in the desired action, such as signing up for the HubPages Service or publishing an article on the HubPages Service.
Author Google AnalyticsThis is used to provide traffic data and reports to the authors of articles on the HubPages Service. (Privacy Policy)
ComscoreComScore is a media measurement and analytics company providing marketing data and analytics to enterprises, media and advertising agencies, and publishers. Non-consent will result in ComScore only processing obfuscated personal data. (Privacy Policy)
Amazon Tracking PixelSome articles display amazon products as part of the Amazon Affiliate program, this pixel provides traffic statistics for those products (Privacy Policy)
ClickscoThis is a data management platform studying reader behavior (Privacy Policy)