I do a lot of shopping for clothes, accessories, and unique birthday presents online, mostly from sites like Etsy. It seems like the best way to buy from independent designers and artists, unless you're lucky enough to have some kind of expo or something in your area. And even then, it's likely a one- or two-day event. Shopping online enables you to purchase things specific to your taste at your own convenience. I've heard some concerns about shipping and the amount of fuel and resources that takes, but I have a similar view on this as I do on public transportation. Those things are going to run anyway. And a shipping truck might have to go a bit out of the way to take stuff to your house, but is that more than the resources you'd use to go somewhere and buy the thing at a store? Especially if it's something you would definitely have to drive home, like a piece of furniture.
Obviously, though, online shopping does cut down on physical activity and social interaction. I just don't think that makes it a bad thing. If you spend less time shopping at stores (including the time it takes to get there and back), that gives you more time to interact with friends and family if that's something that's important to you, and you choose to spend your time that way. WryLilt mentions less time shopping means more time to spend doing things the kids will enjoy. It's really about the balance.
Ultimately, I don't think it's the practice of online shopping that's going to turn people into recluses. It's the unwillingness to maintain balance in their lives.