I always have one reply for people like that:
"If ignorance is bliss, you must be one happy person."
Seriously, it sounds like this chick has some intense personal issues. Maybe she was accused of being lesbian because she licked a frog once and it tasted like chicken. Who knows, but, it doesn't matter. Smile, nod, hand her the "I'm an idiot" card, and walk away.
Life's too short to let idiots waste your time.
...wait, if that's the case, sorry for taking your time.