It seems that some, heart, medicines don't work so well when mixed with grapefruit.
Grapefruit and other citrus fruits can interfere with meds. The chemicals in the fruit can sometimes interfere with medicine taken at a different time, too, so people need to be careful and may have to stop eating grapefruit altogether.
Grapefruit contain a chemicals known as furanocoumarins which interfere with metabolism of medication in the digestive tract leading to possible overdose of the medication. This interaction of grapefruit with certain medication has been discovered to cause adverse health effects some of which are potentially life threatening for example;
and in more severe cases, sudden death.
For more information, check out my hub on the same topic
Grapefruit juice can sometimes increase, or decrease the strength of prescription medication. Dependent on the type of medication. See Chart
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