What causes Polycystic Ovaries ?
Does excess insulin in the body cause PCOs
Does PCOs cause excess insulin in the body?
Or are there any other reason??
When the receptors for insulin are no longer as responsive to the same level of insulin normally produced (downregulation), then there is insulin resistance.
This is characteristic of non insulin dependent diabetes..normally it occurs in adults..adult onset non insulin dependent diabetes mellitus or type 2
There is some correlation between the level of insulin with PCOs, but it is neither deterministic nor direct.
I think this is a helpful site
Polycystic ovaries or PCOS. Is an endocrine problem of the ovaries characterised by these main features : reduced fertility due to lack of ovulation, period problems , excessive male hormones causing acne and hair growth( hirsutism) and central obesity with insulin resistance.
It is largely genetic and can be inherited through mother or father. As the ovaries contain finite number of follicles containing the eggs- many get overstimulated and become cystic but without proper maturation. As all the effects of PCOS are mediated through body fat- losing weight will be the single most important step in reducing/ eliminating the effects.
PCOS does not cause excess insulin but causes insulin resistance. Tissues don't respond the same way to the circulating insulin and leads to high blood sugar just like type II diabetes. Reducing weight improves responsiveness to insulin by decreasing the carbohydrate receptors. We also use anti diabetic drugs such as metformin to treat PCOS.
This is a disease which is now-a-days, found in 6 out of 10 ladies.It ,as per my knowledge, is caused by thick bleeding at the time of periods to the women at any age.It not only comes with severe hormonal changes in the body but also reduces the chances of conceiving at ease.
The thick blood like particles at the time of periods gets clotted at a place in the ovary and with the span of time it enlarges and blocks the regular flow of the periods as well.
The person suffering from the same, might also see an increase in the body weight and even if conceives ,faces a lot of problems at the time of pregnancy.My wife was also suffering from the same disease for which we are consulting a gynecologist,which is very necessary .Also this disease should not be neglected
There is a correlation between insulin resistance and polycystic ovary disease, which means that women who have polycystic ovary syndrome also tend to have insulin resistance. Weight gain and the resultant insulin resistance is thought to be one of several causes of PCOS. Normally, insulin, a hormone, is secreted from the beta cells of the pancreas in response to the presence of an increase in glucose in the blood (glucose is a simple sugar produced by hydrolysis of carbohydrates in the intestines). Insulin is responsible for aiding in the uptake, utilization and storage of glucose throughout the body. Glucose cannot pass through the cell membranes without insulin. When the cells, for a variety of reasons including genetics and stress become resistant to insulin, blood sugar rises in a condition known as insulin resistance. This leads to non-insulin-dependent diabetes (NIDDM), weight gain (due to the disruption in glucose metabolism) and PCOS.
No one knows the exact cause of PCOS. We do know that it comes from problems with hormones, or natural body chemicals. Many girls with PCOS have too much insulin, a hormone that helps turn food into energy. Extra insulin can cause the darkened skin you may have on your neck, behind your knees, and other places. Also, having too much insulin may cause your body to make more of hormones called androgens (say: AN-druh-junz). Although these hormones cause male traits, females have them too. It’s the extra androgen that can lead to acne, excess body hair, weight gain, and irregular periods.
Thank you one and all for taking the time to answer my question.
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